Evidence map›Paper›PMID 41550165›Full record

ArticlePharmaceutical science advances2024

Sclareol exerts an anti-inflammatory effect, possibly through COXs inhibition pathway:

Abdullah Al Shamsh Prottay, Mehedi Hasan Bappi, Md Showkoth Akbor, Afia Ibnath Asha, Md Shimul Bhuia, Aqib Adnan Shafin, Md Nayem Mia, Mohammad S Mubarak, Micheline de Azevedo Lima, Henrique Douglas Melo Coutinho and 1 more

Abstract read
In one paragraph

Article in Pharmaceutical science advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Abdullah Al Shamsh ProttayDepartment of Pharmacy, Bangabandhu Sheikh Mujibur Rahman Science and Technology University, Gopalganj, 8100, Bangladesh.
Mehedi Hasan BappiDepartment of Pharmacy, Bangabandhu Sheikh Mujibur Rahman Science and Technology University, Gopalganj, 8100, Bangladesh.
Md Showkoth AkborDepartment of Pharmacy, Bangabandhu Sheikh Mujibur Rahman Science and Technology University, Gopalganj, 8100, Bangladesh.
Afia Ibnath AshaDepartment of Biochemistry and Molecular Biology, Bangabandhu Sheikh Mujibur Rahman Science and Technology University, Gopalganj, 8100, Bangladesh.
Md Shimul BhuiaDepartment of Pharmacy, Bangabandhu Sheikh Mujibur Rahman Science and Technology University, Gopalganj, 8100, Bangladesh.
Aqib Adnan ShafinDepartment of Applied Chemistry and Chemical Engineering, Bangabandhu Sheikh Mujibur Rahman Science and Technology University, Gopalganj, 8100, Bangladesh.
Md Nayem MiaDepartment of Pharmacy, Bangabandhu Sheikh Mujibur Rahman Science and Technology University, Gopalganj, 8100, Bangladesh.
Mohammad S MubarakDepartment of Chemistry, The University of Jordan, Amman, 11942, Jordan.
Micheline de Azevedo LimaDepartment of Molecular Biology, Federal University of Paraiba - UFPB, João Pessoa, 58051-900, Paraiba, Brazil.
Henrique Douglas Melo CoutinhoDepartment of Biological Chemistry, Regional University of Cariri - URCA, Crato, 63105-000, Ceará, Brazil.
Muhammad Torequl IslamDepartment of Pharmacy, Bangabandhu Sheikh Mujibur Rahman Science and Technology University, Gopalganj, 8100, Bangladesh.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic and severe inflammation results in many diseases and disorders in humans. Currently, available conventional anti-inflammatory drugs have numerous mild-to-severe side effects. Thus, there is a need for safe, effective, affordable, and alternative anti-inflammatory drugs. This study aimed to evaluate the anti-inflammatory effect of sclareol (SCL), a diterpene alcohol that is the principal ingredient in the refined oil of

Indexed as

Anti-Inflammatory effectCyclooxygenaseInflammationMolecular docking simulationSclareol

Identifiers

PMID41550165
PMCPMC12710028

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.