ArticleJournal of ginseng research2026
Ginsenoside Ro alleviated cuproptosis induced by high oxalate via inhibiting zinc transporter ZnT1 in renal tubular epithelial cells.
Article in Journal of ginseng research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Ginsenosides fromJournal of ginseng research · 2026Review
- Regulated Cell Death in Calcium Oxalate Stone Disease: From Tubular Epithelial Injury to Inflammatory Amplification.Journal of inflammation research · 2026Review
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Authors and funding
13 authors.
Funding
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Abstract
Background: Kidney stone disease (KSD), notably characterized by heightened oxidative stress and cell death within renal tubular epithelial cells due to high oxalate. Ginsenoside Ro (Ro), a scarce oleanane-type saponin isolated from Materials and methods: Results: Ro effectively mitigated renal injury induced by Gly in mice. Moreover, it notably ameliorated renal crystal deposition and infiltration of F4/80-positive macrophages observed in Gly mice. Additionally, Conclusion: This study provided evidence that Ro mitigated cuproptosis HK-2 cells induced by high oxalate through inhibiting ZnT1, thus effectively suppressing oxidative stress and crystal deposition triggered by high oxalate.
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