Evidence map›Paper›PMID 41550715›Full record

ArticleiScience2026

Control of renal central carbon metabolism by heme oxygenase-1.

Joel Guerra, Elisa Jentho, Sascha Schäuble, Brendon P Scicluna, Wolfgang Vivas, Dania Martínez-Alarcón, Marco Groth, Emma King, Franziska Röstel, Gianna Hirth and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Joel GuerraDepartment of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Friedrich-Schiller University, Jena, Germany.
Elisa JenthoDepartment of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Friedrich-Schiller University, Jena, Germany.
Sascha SchäubleDepartment of Microbiome Dynamics, Leibniz Institute for Natural Product Research and Infection Biology - Hans-Knöll Institute (Leibniz-HKI), Jena, Germany.
Brendon P SciclunaDepartment of Applied Biomedical Science, Faculty of Health Sciences, Mater Dei Hospital, University of Malta, Msida, Malta.
Wolfgang VivasDepartment of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Friedrich-Schiller University, Jena, Germany.
Dania Martínez-AlarcónInstitute for Infectious Disease and Infection Control, Jena University Hospital, Friedrich-Schiller University, Jena, Germany.
Marco GrothGenome Analysis, Leibniz Institute on Aging - Fritz Lipmann Institute (FLI), Jena, Germany.
Emma KingDepartment of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Friedrich-Schiller University, Jena, Germany.
Franziska RöstelInstitute for Infectious Disease and Infection Control, Jena University Hospital, Friedrich-Schiller University, Jena, Germany.
Gianna HirthLeibniz Institute for Natural Product Research and Infection Biology, Hans-Knöll Institute- HKI, Jena, Germany.
Miguel P SoaresGulbenkian Institute for Molecular Medicine, Lisboa, Portugal.
Thorsten WiechInstitute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Gianni PanagiotouDepartment of Microbiome Dynamics, Leibniz Institute for Natural Product Research and Infection Biology - Hans-Knöll Institute (Leibniz-HKI), Jena, Germany.
Michael BauerDepartment of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Friedrich-Schiller University, Jena, Germany.
Verena HoerrInstitute of Medical Microbiology, Jena University Hospital, Friedrich Schiller University Jena, Jena, Germany.
Sebastian WeisDepartment of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Friedrich-Schiller University, Jena, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metabolic adaptation is an integral part of the organismal stress-response. In this study, we investigate the role of Hmox1 in mediating metabolic adaptation under both physiological and hemolytic stress conditions. Using an inducible

Indexed as

Cell biologyMolecular physiology

Identifiers

PMID41550715
PMCPMC12803938

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.