Evidence map›Paper›PMID 41551003›Full record

ArticleJAR life2026

Introducing the WHO ICOPE approach into HIV care: A perspective on healthy ageing in people living with HIV.

Giovanni Guaraldi, Jovana Milic, Licia Gozzi, Severino Ambrosio, Elisabetta Delmonte, Irene Avanzini, Barbara Castelnuovo, Cristina Mussini

Erratum issuedAbstract read
In one paragraph

Article in JAR life, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Giovanni GuaraldiUniversity of Modena and Reggio Emilia, Italy.
Jovana MilicUniversity of Modena and Reggio Emilia, Italy.
Licia GozziUniversity of Modena and Reggio Emilia, Italy.
Severino AmbrosioUniversity of Modena and Reggio Emilia, Italy.
Elisabetta DelmonteUniversity of Modena and Reggio Emilia, Italy.
Irene AvanziniUniversity of Modena and Reggio Emilia, Italy.
Barbara CastelnuovoThe Infectious Diseases Institute, Makerere University College of Health Sciences, Kampala, Uganda.
Cristina MussiniUniversity of Modena and Reggio Emilia, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The ageing of people living with HIV (PWH) presents unique clinical and public health challenges that are not fully addressed by current care models. Objective: This Perspective paper aims to explore the feasibility and added value of introducing the World Health Organization (WHO) Integrated Care for Older People (ICOPE) framework and guidelines into HIV care models, using the lens of intrinsic capacity (IC) and functional ability to reframe how age-related conditions are managed. In particular, we discuss how HIV services can adopt intrinsic capacity (IC) assessments and function-centered care as a scalable strategy to promote healthy ageing. Methods: This is a narrative and conceptual Perspective based on literature review, expert consultation, and clinical case examples, including the Modena HIV Metabolic Clinic and experiences from resource-limited settings. Results: The ICOPE approach offers a feasible, person-centred framework for identifying and managing early declines of IC across six domains. ICOPE facilitates timely interventions at the primary health care level. HIV care services and systems, already oriented towards longitudinal and multidisciplinary management, are uniquely positioned to pioneer ICOPE implementation. Conclusion: HIV medicine may serve as a model for expanding the integration of the ICOPE approach across chronic diseases, especially in low-resource settings where primary care structures must address age-related vulnerability. Adopting ICOPE can promote healthy ageing in PWH and beyond.

Indexed as

FrailtyHealthy ageingHIVICOPEIntrinsic capacity

Identifiers

PMID41551003
PMCPMC12809131

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.