SynthesisFrontiers in neurology2025
The correlation between perceived psychosocial stress and stroke: a meta-analysis.
Synthesis in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: This meta-analysis aimed to evaluate the association between perceived psychosocial stress and stroke. Methods: We systematically searched PubMed, Web of Science, Embase and Cochrane Library until March 2025. Published studies reporting adjusted odds ratios (ORs), hazard ratios (HRs), or relative risks (RRs) for stroke in perceived psychosocial stress versus non-perceived psychosocial stress individuals and perceived stress in stroke versus non-stroke individuals were included. A random-effects model was used to pool effect estimates, with heterogeneity assessed via the chi-square test based on Cochrane Q statistics. Subgroup evaluations were conducted for stroke type (ischemic/hemorrhagic), region, and sex. Results: Eleven case-control studies were included, with the case group comprising stroke patients ( Conclusion: Meta-analysis of case-control studies demonstrated that perceived psychosocial stress is a risk factor for stroke, ischemic stroke, and hemorrhagic stroke in both Europe/America and Asia, regardless of sex, particularly among stroke patients Age < 50. However, prospective cohort studies revealed no significant differences in the probability of stroke, ischemic stroke, or hemorrhagic stroke between the perceived stress and control groups across regions (Europe/America and Asia) and Sex (males and females). Meta-analysis registration: PROSPERO2025; https://www.crd.york.ac.uk/PROSPERO/view/CRD420251012354.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.