Evidence map›Paper›PMID 41551845›Full record

ArticleJournal of environmental health science & engineering2026

Glyphosate exposure, bone mineral density, osteoporosis, and fractures in the United States population.

Naila Khalil, Latifa Hamdaoui, Alan Ducatman, Antti Koskela, Tarek Rebai, Miryoung Lee, Ramzi W Nahhas

Abstract read
In one paragraph

Article in Journal of environmental health science & engineering, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Naila KhalilDepartment of Population and Public Health Sciences, Boonshoft School of Medicine, Wright State University, 2555 University Blvd., Suite 210, Fairborn, OH 45324 USA.ORCID 0000-0002-7868-7565
Latifa HamdaouiLaboratory of induced and developmental diseases LR19ES12, Sfax Faculty of Medicine, University of Sfax, Sfax, 3029 Tunisia.
Alan DucatmanSchool of Public Health, West Virginia University, Morgantown, WV 26506 USA.
Antti KoskelaResearch Unit of Translational Medicine, Faculty of Medicine, University of Oulu, Wellbeing Services County of North Ostrobothnia, Oulu, Finland.
Tarek RebaiLaboratory of induced and developmental diseases LR19ES12, Sfax Faculty of Medicine, University of Sfax, Sfax, 3029 Tunisia.
Miryoung LeeDepartment of Epidemiology, Human Genetics and Environmental Sciences, The University of Texas Health Sciences Center at Houston, 780 Ringgold Road, Brownsville, TX 78520‑4979 USA.
Ramzi W NahhasDepartment of Population and Public Health Sciences, Boonshoft School of Medicine, Wright State University, 2555 University Blvd., Suite 210, Fairborn, OH 45324 USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Following reports of an adverse link between glyphosate and bone mineral density (BMD), this cross-sectional study extended the investigation between glyphosate exposure and BMD to include osteoporosis, and fractures, with a focus on the high risk, post-menopausal female subgroup. Methods: Cross-sectional data from 2,710 participants of the US National Health and Nutrition Examination Survey aged 8-59 years from 2013 to 2018 were used to assess associations between urinary glyphosate concentration (µg/L) and BMD (g/cm Results: There was a negative association between glyphosate and BMD in the entire population (Whole Body BMD slope = -0.018; 95% CI = -0.027, -0.010; Conclusions: Results are internally consistent and align with existing literature concerning toxicity of glyphosate on bone and extend it to include adverse impact on osteoporosis and fractures. Given the cross-sectional design and single point of sampling, longitudinal studies with repeated sampling are recommended to evaluate causation.

Indexed as

Bone mineral densityChildrenFracturesMenopauseOsteoporosisSex differences

Identifiers

PMID41551845
PMCPMC12811184

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.