Evidence map›Paper›PMID 41552099›Full record

ArticleCureus2025

Acute Promyelocytic Leukemia Presenting as Spontaneous Abortion Amidst Tropical Fever Season: A Diagnostic Challenge.

Ambadas Rathod, Monica Gupta, Anshu Palta

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ambadas RathodGeneral Medicine, Government Medical College and Hospital, Chandigarh, Chandigarh, IND.
Monica GuptaGeneral Medicine, Government Medical College and Hospital, Chandigarh, Chandigarh, IND.
Anshu PaltaPathology, Government Medical College and Hospital, Chandigarh, Chandigarh, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute myeloid leukemia (AML) is a hematologic malignancy with diverse and often nonspecific clinical manifestations. This report discusses a 30-year-old female presenting with fever for six days and per vaginal (PV) bleeding persisting for three days during the tropical fever season. Initial evaluation indicated pancytopenia, leading to considerations of infectious, nutritional, or hematologic etiologies. A detailed history revealed 10 weeks of amenorrhea with a positive urine pregnancy test (UPT) confirmed pregnancy, which was further supported by ultrasonography (USG), suggesting incomplete abortion. However, over the next few hours, she passed multiple clots per vagina, and a repeat USG confirmed that she had sustained a complete abortion. Despite multiple transfusions, pancytopenia persisted, prompting a bone marrow examination that confirmed acute promyelocytic leukemia (APL), a subtype of AML. This case underscores that unexplained pancytopenia persisting beyond seven days after pregnancy loss warrants early bone marrow evaluation to rule out hematologic malignancies, as AML can present with gynecological symptoms in young females and requires prompt diagnosis.

Indexed as

acute myeloid leukemia (aml)acute promyelocytic leukemia (apl)bleeding per vaginapancytopeniaspontaneous abortion

Identifiers

PMID41552099
PMCPMC12807448

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.