ArticleAmerican journal of translational research2025
Impacts of sufentanil/remifentanil plus sevoflurane versus propofol in adults undergoing laparoscopic herniorrhaphy.
Article in American journal of translational research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
objectiveTo retrospectively explore how sevoflurane + sufentanil/remifentanil versus propofol + sufentanil/remifentanil impacts clinical outcomes in laparoscopic herniorrhaphy-treated adults.
methodsWe enrolled 102 adult patients grouped into propofol (n=50) and sevoflurane (n=52) groups. Inter-group comparisons were made regarding operative duration, time to induction, extubation, emergence, and consciousness recovery, agitation incidence, first ambulation time, length of stay, and gastrointestinal recovery. Adverse events, hemodynamic parameters, as well as preoperative and postoperative stress markers, inflammatory cytokines, and pain mediators, were also discussed.
resultsThe sevoflurane group had statistically shorter times to extubation, consciousness recovery, first ambulation, and gastrointestinal restoration, along with lower agitation and overall adverse event rates. Shorter anesthesia emergence time and more stable hemodynamic parameters were also found in patients receiving sevoflurane compared to the propofol cohort. Better performance in postoperative stress response, inflammatory markers, and pain mediators (except for a milder decrease in β-endorphin [β-EP]) was also determined in sevoflurane-treated patients. No notable intergroup differences were identified in the durations of surgery, induction, and hospitalization.
conclusionCompared to the propofol combination, the sevoflurane-sufentanil/remifentanil regimen applied to adult laparoscopic hernia repair patients contributed to superior clinical outcomes.
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