Evidence map›Paper›PMID 41552497›Full record

ArticleACS omega2026

Topical Application of Artesunate Ameliorates Psoriatic Keratinization and Inflammation via Molecular Modulations Based on Both Human and Mouse Models.

Zhong-Zhou Huang, Ying-Yu Wang, Yu Xiao, Ji Yang, Wei-Guo Wan, Ping Huang, Qing Guo, He-Jian Zou, Xue Yang

Abstract read
In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zhong-Zhou HuangDepartment of Rheumatology, Huashan Hospital, Fudan University, Shanghai 200040, China.
Ying-Yu WangDepartment of Rheumatology, Huashan Hospital, Fudan University, Shanghai 200040, China.
Yu XiaoDepartment of Rheumatology, Huashan Hospital, Fudan University, Shanghai 200040, China.
Ji YangDepartment of Dermatology, Zhongshan Hospital, Fudan University, Shanghai 200030, China.
Wei-Guo WanDepartment of Rheumatology, Huashan Hospital, Fudan University, Shanghai 200040, China.
Ping HuangDepartment of Dermatology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou 510120, China.ORCID https://orcid.org/0000-0002-6333-8338
Qing GuoDepartment of Dermatology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou 510120, China.
He-Jian ZouDepartment of Rheumatology, Huashan Hospital, Fudan University, Shanghai 200040, China.
Xue YangDepartment of Rheumatology, Huashan Hospital, Fudan University, Shanghai 200040, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Artesunate (ART), a drug renowned for its anti-inflammatory and antiproliferative properties, shows promise in psoriasis treatment by potentially modulating autoimmune responses. This study evaluated the efficacy of ART in an imiquimod (IMQ)-induced mouse psoriatic model via topical application and intraperitoneal injection, alongside in vitro investigations using a HaCaT cell-based model. Our results demonstrated that topical ART application significantly alleviated psoriatic inflammation and hyperkeratinization and reduced Th17 and IL-17A

Identifiers

PMID41552497
PMCPMC12809316

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.