SynthesisNeurogastroenterology and motility2026
Wearable-Based Monitoring of Autonomic and Gastrointestinal Function in Disorders of Gut-Brain Interaction: A Systematic Review and Meta-Analyses.
Synthesis in Neurogastroenterology and motility, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Wearable-Based Monitoring of Autonomic and Gastrointestinal Function in Disorders of Gut-Brain Interaction: A Systematic Review and Meta-Analyses.Neurogastroenterology and motility · 2026Pooled it
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
backgroundAutonomic nervous system (ANS) activity is implicated in the pathogenesis of disorders of gut-brain interaction (DGBI). Technological advances enable more accurate investigation of ANS function.
aimThis study aimed to evaluate the clinical utility of wearable devices in monitoring autonomic and gastrointestinal (GI) function in DGBI.
methodsA systematic search identified studies in adults with DGBI using wearables to assess heart rate variability (HRV), sleep, skin conductance, or gastric myoelectric activity as clinical readouts for ANS and GI function. The review provides an overview of available devices, while the meta-analysis evaluates consistency in detecting differences between DGBI and healthy controls (HCs). Associations between autonomic function and GI symptom severity were explored. Methodological quality was assessed using the Cochrane risk of bias tool and ROBINS-I. Meta-analyses used random-effects models with standardized mean differences (SMDs).
resultsThirty-six studies (3 RCTs, 33 observational) involving 3986 DGBI patients were included (HRV: n = 16, sleep: n = 7, gastric myoelectric activity: n = 14, skin conductance: n = 0). Meta-analyses showed lower Root Mean Square of Successive Differences (SMD = -0.503, SE 0.189, 95% CI [-0.873, -0.132]) and percentage of successive RR intervals differing by > 50 ms (SMD = -0.430, SE 0.176, 95% CI [-0.775, -0.085]), reflecting HRV alterations in DGBI versus HCs. No consistent differences were found for other metrics, except normal gastric slow waves (SMD = -0.722, SE 0.216, 95% CI [-1.146, -0.298]). Heterogeneous ANS-symptom associations precluded definitive conclusions.
conclusionsWearables show potential for detecting altered ANS and GI function in DGBI, particularly via HRV. Result variability highlights need for further research to confirm accuracy and clinical utility.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.