Evidence map›Paper›PMID 41554947›Full record

ArticleScientific reports2026

Serum Mac-2 binding protein glycosylation isomer in predicting hepatocellular carcinoma occurrence among patients with direct-acting antiviral-induced HCV cure.

Yu-Ping Chang, Yun-Chu Chen, Tung-Hung Su, Shang-Chin Huang, Tai-Chung Tseng, Pei-Jer Chen, Chun-Jen Liu, Jia-Horng Kao, Chen-Hua Liu

Abstract read
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In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yu-Ping Chang *Department of Internal Medicine, National Taiwan University Biomedical Park Hospital Park Hospital, Hsin-Chu, Taiwan.
Yun-Chu Chen *Department of Internal Medicine, National Taiwan University Hospital, 7 Chung-Shan South Road, Taipei, 10002, Taiwan.
Tung-Hung SuDepartment of Internal Medicine, National Taiwan University Hospital, 7 Chung-Shan South Road, Taipei, 10002, Taiwan.
Shang-Chin HuangHepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan.
Tai-Chung TsengDepartment of Internal Medicine, National Taiwan University Hospital, 7 Chung-Shan South Road, Taipei, 10002, Taiwan.
Pei-Jer ChenDepartment of Internal Medicine, National Taiwan University Hospital, 7 Chung-Shan South Road, Taipei, 10002, Taiwan.
Chun-Jen LiuDepartment of Internal Medicine, National Taiwan University Hospital, 7 Chung-Shan South Road, Taipei, 10002, Taiwan.
Jia-Horng KaoDepartment of Internal Medicine, National Taiwan University Hospital, 7 Chung-Shan South Road, Taipei, 10002, Taiwan.
Chen-Hua LiuDepartment of Internal Medicine, National Taiwan University Hospital, 7 Chung-Shan South Road, Taipei, 10002, Taiwan. jacque_liu@mail2000.com.tw.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mac-2-binding protein glycosylation isomer (M2BPGi), a promising biomarker for predicting hepatocellular carcinoma (HCC), was evaluated in predicting HCC occurrence after hepatitis C virus (HCV) cure with direct-acting antivirals (DAAs). 704 eligible patients underwent biannual surveillance, including alpha-fetoprotein (AFP) and liver imaging studies, to detect HCC occurrence. Serum M2BPGi levels were measured at both pretreatment and sustained virologic response (SVR

Indexed as

Antigens, NeoplasmAntiviral AgentsCarcinoma, HepatocellularHepatitis C, ChronicLiver NeoplasmsMembrane GlycoproteinsAgedalpha-FetoproteinsBiomarkers, TumorFemaleGlycosylationHepacivirusHumansIncidenceMaleMiddle Agedalpha-FetoproteinsAntigens, NeoplasmAntiviral AgentsBiomarkers, TumorMembrane GlycoproteinsTAA90K protein, humanBiomarkersHepatitis C virusHepatocellular carcinomaMac-2-binding protein glycosylation isomer

Identifiers

PMID41554947
PMCPMC12894946

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.