ArticleBMC cardiovascular disorders2026
Cardiac troponin and subclinical cardiovascular dysfunction in metabolic syndrome: a retrospective analysis based on two diagnostic definitions.
Article in BMC cardiovascular disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Systemic Inflammatory Markers in Patients with Metabolic Syndrome with and Without Dry Eye Disease: An Observational Comparative Study.Diagnostics (Basel, Switzerland) · 2026Article
- Associations of occupational exposure to multiple heavy metals and metabolic syndrome among metal foundry workers: a cross‑sectional study.BMC endocrine disorders · 2026Article
- Intraoperative Terlipressin During Liver Transplantation Is Associated with Reduced Vasoactive Requirements and Lower Postoperative Troponin Release.Journal of clinical medicine · 2026Article
- Incidence of Acute Myocardial Infarction in Hungary: A Nationwide Study.Journal of clinical medicine · 2026Article
- A linear association between serum uric acid and 28-day and 90-day mortality after veno-arterial extracorporeal membrane oxygenation in patients with acute myocardial infarction complicated by cardiogenic shock.Frontiers in cardiovascular medicine · 2026Article
- Associations of High-Sensitivity Cardiac Troponin T, D-Dimer, and N-Terminal Pro-B-Type Natriuretic Peptide with Subclinical Cardiovascular Dysfunction in the General Population: A Retrospective Cross-Sectional Study.Vascular health and risk management · 2026Article
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Authors and funding
5 authors.
Funding
Abstract
backgroundSerum high-sensitivity cardiac troponin T concentration (hs-cTnT) belongs to key markers of myocardial damage. Its role in screening for subclinical cardiovascular (CV) dysfunction remains unclear. Metabolic syndrome (MetS) is a constellation of coexisting disorders that lead to increased CV risk. There are various criteria for diagnosing MetS.
objectiveThe purpose of this study was to analyze the correlation between hs-cTnT and selected parameters of subclinical CV dysfunction in individuals with and without MetS, taking into account the influence of the adopted MetS definition on these relationships. PATIENTS AND
methodsThe study consisted of a retrospective analysis of data from 113 patients (mean age 60.14 ± 16.44; 61.95% females) without symptoms of acute illness. Echocardiography, Doppler ultrasound of the carotid arteries and lower extremities arteries, central blood pressure, and pulse wave velocity (PWV) measurement, as well as ankle-brachial index (ABI) and toe-brachial index (TBI) measurements, were used to assess features of CV dysfunction. The criteria included in the 2009 consensus of scientific societies and those proposed by Polish experts in 2022 were independently applied to diagnose MetS and the results were analyzed.
resultsIndividuals with MetS were characterized by significantly more severe subclinical CV dysfunction, and the differences were more pronounced when using the 2022 definition of Polish experts. hs-cTnT significantly correlates with parameters of CV dysfunction (left ventricle diastolic dysfunction, vascular stiffness, and subclinical atherosclerosis) in patients with and without MetS. Interaction analysis and multivariate analysis did not find any significant differences between individuals with and without MetS in the correlation between hs-cTnT and the analyzed CV dysfunction parameters.
conclusionSome significant correlations were found between hs-cTnT and selected CV dysfunction parameters in patients with MetS. However, hs-cTnT did not consistently demonstrate superior diagnostic utility for detecting subclinical CV damage in individuals with MetS compared to those without MetS.
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