Evidence map›Paper›PMID 41555261›Full record

SynthesisBMC nephrology2026

Incidence of acute kidney injury and associated mortality in Nigeria: systematic review and meta-analysis.

Oluseyi Ademola Adejumo, Imuetinyan Rahsida Edeki, Olalekan Ezekiel Ojo, Manmak Mamven, Bala Waziri, Emmanuel Effa, Timothy Olusegun Olanrewaju, Ogochukwu Chinedum Okoye, Dapo Sunday Oyedepo, Muhammad Aliyu Makusidi and 6 more

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in BMC nephrology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Oluseyi Ademola AdejumoDepartment of Internal Medicine, University of Medical Sciences, Ondo City, Ondo State, Nigeria.
Imuetinyan Rahsida EdekiDepartment of Internal Medicine, University of Benin Teaching Hospital, Benin City, Edo State, Nigeria.
Olalekan Ezekiel OjoRenal Unit, Department of Internal Medicine, Federal Medical Centre, Owo, Ondo State, Nigeria.
Manmak MamvenDepartment of Internal Medicine, University of Abuja, Abuja, Nigeria.
Bala WaziriIbrahim Badamasi Babaginda Specialist Hospital, Minna, Niger State, Nigeria.
Emmanuel EffaDepartment of Internal Medicine, University of Calabar, Calabar City, Cross River State, Nigeria.
Timothy Olusegun OlanrewajuDivision of Nephrology, Department of Medicine, University of Ilorin, Ilorin, Kwara State, Nigeria.
Ogochukwu Chinedum OkoyeDepartment of Internal Medicine, Faculty of Clinical Medicine, Delta State University, Abraka, Delta State, Nigeria.
Dapo Sunday OyedepoDivision of Nephrology, Department of Medicine, University of Ilorin, Ilorin, Kwara State, Nigeria.
Muhammad Aliyu MakusidiDepartment of Internal Medicine, Usmanu Danfodiyo University, Sokoto City, Sokoto State, Nigeria.
Udeme-Abasi Udoudo NelsonDepartment of Internal Medicine, University College Hospital, Ibadan, Oyo State, Nigeria.
Oyinkansola Aderinsola OmolojaDepartment of Internal Medicine, University of Medical Sciences, Ondo City, Ondo State, Nigeria.
Muzamil Olamide HassanDepartment of Medicine, Obafemi Awolowo University, Ile-Ife, Osun State, Nigeria.
Bolanle Aderonke OmotosoDepartment of Medical Pharmacology and Therapeutics, Obafemi Awolowo University, Ile-Ife, Osun State, Nigeria.
Udeme Ekpenyong EkrikpoDepartment of Internal Medicine, University of Uyo, Uyo, Akwa Ibom State, Nigeria. udekrikpo@gmail.com.ORCID 0000-0002-3911-5564
Fatiu Abiola ArogundadeFederal University of Medicine and Medical Sciences, Abeokuta City, Ogun State, Nigeria.

Funding

Deep South KUH Premier Research - Interdisciplinary Mentored Education (PRIME) Training CoreTL1DK139566 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI DAVID M POLLOCK · 2023 to 2026
$3.6M
Deep South KUH Premier Research- Interdisciplinary Mentored Education (PRIME) Networking CoreU2CDK133422 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Kelly Hyndman · 2023 to 2026
$2.8M
NIDDK NIH HHS TL1 DK139566NIDDK NIH HHS U2C DK133422
6 · The paper itself

Abstract

backgroundThe burden of acute kidney injury (AKI) in low- and middle-income countries is frequently underestimated, often due to limited diagnostic resources and underreporting. Information about the burden of AKI would help inform the implementation of health policies and improve the allocation of health resources aimed at enhancing patient outcomes. This study determined the pooled incidence of AKI and associated mortality in Nigeria.

methodA systematic search of PubMed, African Journals Online (AJOL), and Google Scholar was conducted to identify relevant studies on AKI in both adult and paediatric populations in Nigeria between 1980 and 2024. Case reports, case series, and abstracts without full text on AKI were excluded. The pooled incidence of AKI and the associated all-cause mortality rate were estimated using meta-analytic methods. The Joanna-Briggs scoring was used for risk bias assessment. The study protocol was registered with PROSPERO (CRD42024620822).

resultsThe initial systematic literature search identified 384 articles from which 44 eligible hospital-based studies involving 123,324 participants were included. The median age of the study participants was 31.1 years, and the median proportion of females was 42.9%. The overall pooled incidence of AKI in this study was 15.0% [CI: 12.0-18.0%], based on 44 studies, with I LIMITATIONS OF THE STUDY: The review included only hospital-based studies, and high heterogeneity was observed in the studies. Therefore, the results should be interpreted with caution.

conclusionThe incidence and mortality rates of AKI in Nigeria are high. Prompt and adequate treatment of the underlying and preventable causes may reduce the disease burden.

Indexed as

Acute Kidney InjuryFemaleHumansIncidenceNigeriaAcute kidney injuryIncidenceMortalityNigeriaSystematic review

Identifiers

PMID41555261
PMCPMC12973764

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.