Evidence map›Paper›PMID 41555300›Full record

ArticleBMC complementary medicine and therapies2026

Phytochemical profiling and bioactivity assessment of the ethanol extract of Lannea schimperi bark: antioxidant, antiradical, and antimicrobial potentials.

Charles O Joseph

Abstract read
In one paragraph

Article in BMC complementary medicine and therapies, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Charles O JosephDepartment of Crop Sciences and Beekeeping Technology, College of Agriculture and Food Technology, University of Dar Es Salaam, P.O Box 35091, Dar Es Salaam, Tanzania. jcharles@udsm.ac.tz.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The antioxidant, antiradical, and antimicrobial potentials of Lannea. schimperi (Hochst. ex A.Rich.) Engl. extracts are well documented. However, few studies have integrated these evaluations with phytochemical profiling. In this study, the antimicrobial activity, minimum inhibitory concentrations (MIC), antioxidant and antiradical activities, and phytochemical composition of L. schimperi bark extracts were examined. The inhibition zones ranged from 8.3 ± 0.5 mm to 18.3 ± 1.2 mm. The MIC values, determined spectrophotometrically, were as follows: Candida albicans (500 ± 0.0 µg/mL), Pseudomonas aeruginosa (250 ± 0.1 µg/mL), Bacillus subtilis (125.0 ± 18.4 µg/mL), Escherichia coli (125.0 ± 9.2 µg/mL), and Staphylococcus aureus (62.5 ± 18.4 µg/mL). The total phenolic and flavonoid contents were 256.94 ± 6.48 mg GAE/g and 29.22 ± 0.6 mg RE/g respectively. Antiradical activity ranged from 3.68 ± 0.4 to 13.86 ± 0.22 units per mg of extract, and from 320.2 ± 6 to 386.6 ± 23 units per gram of raw material. GC–MS analysis identified several saturated fatty acids and esters, including butanedioic acid (2.2%), n-tridecanoic acid (1.7%), bis(2-ethylhexyl) adipate (0.8%), n-pentadecanoic acid (3.9%), heptadecanoic acid (61.7%), 11-methyloctadecanoic acid (10.5%), nonadecanoic acid (7.9%), and 11-eicosenoic acid (1.4%). LC–MS analysis detected catechin (83.81%), piperine (92.93%), 9,10-dihydroxy-12Z-octadecenoic acid (83.19%), and galactonic acid (79.78%). Overall, the analysis of L. schimperi bark extracts highlights its significant antimicrobial, antioxidant, and phytochemical properties, supporting its potential as a natural therapeutic agent and further validate its traditional use in treating various ailments.

Indexed as

AnacardiaceaeAnti-Infective AgentsAntioxidantsPhytochemicalsPlant ExtractsCandida albicansFlavonoidsMicrobial Sensitivity TestsPhenolsPlant BarkAnti-Infective AgentsAntioxidantsFlavonoidsPhenolsPhytochemicalsPlant ExtractsAntimicrobialAntioxidantGC–MSLannea schimperiLC–MSPhytochemical profiling

Identifiers

PMID41555300
PMCPMC12955318

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.