Evidence map›Paper›PMID 41555312›Full record

ArticleBMC oral health2026

Correlation between disc-condyle relationship and the efficacy of conservative treatment in patients with anterior disc displacement without reduction.

Xingyu Lyu, Yuke Shi, Ruiye Bi, Mingjun Ren, Songsong Zhu, Pinyin Cao

Abstract read
In one paragraph

Article in BMC oral health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xingyu LyuDepartment of Orthognathic and TMJ Surgery, State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, Sichuan, China.
Yuke ShiDepartment of Orthodontics, State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, Sichuan, China.
Ruiye BiDepartment of Orthognathic and TMJ Surgery, State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, Sichuan, China.
Mingjun RenDepartment of Orthognathic and TMJ Surgery, State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, Sichuan, China.
Songsong ZhuDepartment of Orthognathic and TMJ Surgery, State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, Sichuan, China. ZSS_1977@163.com.
Pinyin CaoDepartment of Orthognathic and TMJ Surgery, State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, Sichuan, China. woshicin@126.com.

Funding

National Key Research and Development Program of China No. 2023YFC2509200 to SZNational Natural Science Foundation of China No.82270999, 82471002 to RBNational Natural Science Foundation of China No. 82301109 to PCNational Natural Science Foundation of China No. W251100, U23A20446 to SZthe Clinical Research Program of West China Hospital of Stomatology No. LCYJ2023-DL-5 to RB
6 · The paper itself

Abstract

objectiveTo investigate the correlation between the positional relationship of the TMJ disc and condyle on MRI and the therapeutic efficacy of temporomandibular intra-articular injection in patients with Anterior Disc Displacement without Reduction(ADDWoR). MATERIALS AND

methodsRetrospectively included 74 patients (74 joints) with ADDWoR who completed four temporomandibular intra-articular injections and underwent 3-month follow-up. On MRI images at closed-mouth and maximum-opening positions, measured the disc angle relative to the condyle before treatment(Angle), and the disc anterior displacement distance (Distance). Spearman’s rank correlation analysis assessed monotonic relationships between variables. Locally Estimated Scatterplot Smoothing(LOESS) fitted nonlinear trends, with statistical significance tested via the smoothing term in Generalized Additive Models (GAM). The R² value of the LOESS fit was calculated to quantify model explanatory power. Additionally, to determine the optimal cutoff value of the Angle metric for predicting treatment efficacy, ROC curve analysis was performed, and the optimal discriminative threshold was identified by maximizing the Youden index.

resultsScatter plots reveal an S-shaped correlation between Angle and maximum mouth opening (MMO) before and after treatment, while Angle shows a W-shaped correlation with ∆MMO and ∆VAS. ROC curve analysis and determination of the optimal cutoff point by maximizing the Youden index indicate that the optimal cutoff is -20.65°.

conclusionsThis study establishes an MRI based cutoff of -20.65° for the Angle as a preliminary indicator that may help clinicians rapidly identify ADDWoR patients(Patients with Angle < − 20.65°) unlikely to benefit from Sodium Hyaluronate injections(HA). CLINIC RELEVANCE: An MRI derived disc angle relative to the condyle of ≤ − 20.65° can serve as a preliminary indicaor of ADDWoR patients who are unlikely to benefit from temporomandibular intra-articular HA injections, thereby facilitating timely referral for other intervention and safeguarding the optimum window for osteoarthritic change management.

Indexed as

Conservative TreatmentJoint DislocationsMandibular CondyleTemporomandibular Joint DiscTemporomandibular Joint DisordersAdultFemaleHumansInjections, Intra-ArticularMagnetic Resonance ImagingMaleMiddle AgedRetrospective StudiesTreatment OutcomeAnterior disc displacementClinical decisionsDiagnostic accuracyIntra-articular injectionsTemporomandibular disorders

Identifiers

PMID41555312
PMCPMC12903565

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.