ArticleEuropean journal of medical research2026
The association between blood urea nitrogen to serum albumin ratio and all-cause mortality in critically ill patients with atrial fibrillation.
Article in European journal of medical research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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5 authors.
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Abstract
backgroundBlood urea nitrogen to serum albumin ratio (BAR) is an emerging biomarker that has been associated with sepsis, heart failure, and coronary artery disease. Nevertheless, few studies focus on its association with the prognosis of atrial fibrillation (AF).
methodsThis retrospective study utilized data from the Medical Information Mart for Intensive Care-IV (MIMIC-IV) database. Participants were categorized into three groups based on the BAR tertiles. The Kaplan-Meier analysis was performed to demonstrate the survival rates among three groups. Cox proportional hazards regression and restricted cubic spline (RCS) were conducted to explore the correlation between BAR and all-cause mortality.
results1523 AF patients were enrolled in this study, with a median age of 73.8 years, of whom 933 (61.3%) were male. The Kaplan-Meier analysis indicated that patients with elevated BAR represented an increased incidence of 28-day and 365-day all-cause mortality. The Cox proportional hazards regression analysis revealed that patients with the highest BAR were independently related to an elevated risk of 28-day (HR, 2.14 [95% CI 1.54 ~ 2.96]; P < 0.001) and 365-day (HR, 2.20 [95% CI 1.72 ~ 2.83]; P < 0.001) all-cause mortality after adjusting for confounding factors. Nonlinear relationships were observed between BAR and 28-day and 365-day all-cause mortality based on the RCS analysis.
conclusionsBAR may serve as an indicator for risk stratification in critically ill AF patients.
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