Evidence mapPaperPMID 41555688Full record

ReviewObesity reviews : an official journal of the International Association for the Study of Obesity2026

Maternal Obesity and MicroRNAs in Breast Milk: Implications for Infant Developmental Programming.

Gyslane M Santos, Fabíola Isabel Suano de Souza, Luciana P Pisani

Abstract readReview
In one paragraph

Review in Obesity reviews : an official journal of the International Association for the Study of Obesity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Gyslane M SantosDepartment of Bioscience, Federal University of São Paulo (UNIFESP), Santos, São Paulo, Brazil.
Fabíola Isabel Suano de SouzaDepartment of Pediatrics, Federal University of São Paulo, São Paulo, Brazil.
Luciana P PisaniDepartment of Bioscience, Federal University of São Paulo (UNIFESP), Santos, São Paulo, Brazil.ORCID 0000-0001-6579-6167

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 307305/2023-6
6 · The paper itself

Abstract

This review explores the relationship between maternal obesity and alterations in the expression of microRNAs (miRNAs) in breast milk, highlighting how these changes may influence the developmental programming of the infant. Evidence suggests that maternal obesity can affect the bioactive composition of breast milk, including miRNA profiles, which are key regulators of metabolic and immune pathways in early life. Specific miRNAs, such as miR-148a and miR-30b, have been identified as modulators of metabolic processes, potentially impacting offspring growth, energy balance, and long-term health outcomes. Additionally, maternal factors such as prepregnancy BMI and dietary patterns play a crucial role in shaping milk composition. Understanding these complex interactions is essential for informing nutritional strategies aimed at supporting optimal infant development and preventing chronic diseases later in life.

Indexed as

Child DevelopmentMicroRNAsMilk, HumanObesityPregnancy in ObesityDevelopmental Origins of Health and DiseaseFemaleHumansInfantInfant, NewbornMaternal Nutritional Physiological PhenomenaPregnancyMicroRNAsbreastmilkdevelopmental programmingDOHaDmiRNAobesity

Identifiers

PMID41555688
PMCPMC13243345

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.