Evidence mapPaperPMID 41555856Full record

ArticleExtracellular vesicles and circulating nucleic acids2025

Comparative analysis of adipose-, bone marrow-, and amniotic membrane-derived MSC secretomes and EVs reveals shared and source-specific therapeutic signatures for osteoarthritis.

Enrico Ragni, Andrea Papait, Michela Maria Taiana, Paola De Luca, Giulio Grieco, Elsa Vertua, Pietro Romele, Antonietta Rosa Silini, Ornella Parolini, Laura de Girolamo

Abstract read
In one paragraph

Article in Extracellular vesicles and circulating nucleic acids, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Enrico RagniIRCCS Ospedale Galeazzi - Sant'Ambrogio, Laboratorio di Biotecnologie Applicate all'Ortopedia, Milano 20157, Italy.
Andrea PapaitDipartimento di Scienze della Vita e Sanità Pubblica, Università Cattolica del Sacro Cuore, Roma 00168, Italy.
Michela Maria TaianaIRCCS Ospedale Galeazzi - Sant'Ambrogio, Laboratorio di Biotecnologie Applicate all'Ortopedia, Milano 20157, Italy.
Paola De LucaIRCCS Ospedale Galeazzi - Sant'Ambrogio, Laboratorio di Biotecnologie Applicate all'Ortopedia, Milano 20157, Italy.
Giulio GriecoIRCCS Ospedale Galeazzi - Sant'Ambrogio, Laboratorio di Biotecnologie Applicate all'Ortopedia, Milano 20157, Italy.
Elsa VertuaCentro di Ricerca E. Menni, Fondazione Poliambulanza Istituto Ospedaliero, Brescia 25124, Italy.
Pietro RomeleCentro di Ricerca E. Menni, Fondazione Poliambulanza Istituto Ospedaliero, Brescia 25124, Italy.
Antonietta Rosa SiliniCentro di Ricerca E. Menni, Fondazione Poliambulanza Istituto Ospedaliero, Brescia 25124, Italy.
Ornella ParoliniDipartimento di Scienze della Vita e Sanità Pubblica, Università Cattolica del Sacro Cuore, Roma 00168, Italy.
Laura de GirolamoIRCCS Ospedale Galeazzi - Sant'Ambrogio, Laboratorio di Biotecnologie Applicate all'Ortopedia, Milano 20157, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

chondroprotectionextracellular vesiclesMesenchymal stromal cellsmiRNAsosteoarthritisparacrine signalingsecretometissue regeneration

Identifiers

PMID41555856
PMCPMC12812444

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.