ArticleWorld journal of psychiatry2026
Association between anxiety, depression, and fatigue in elderly patients with Parkinson's disease.
Article in World journal of psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
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3 authors.
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Abstract
backgroundParkinson's disease (PD) is a common neurodegenerative disorder in the elderly population. Non-motor symptoms such as anxiety and depression are often subtle, hindering early detection and intervention, yet they markedly affect quality of life and clinical outcomes.
aimTo investigate the prevalence of anxiety and depression in elderly PD patients, identify associated risk factors, and assess their relationship with fatigue severity.
methodsA cross-sectional analysis was conducted in 123 elderly PD patients treated at The Second Rehabilitation Hospital of Shanghai between January 2023 and December 2024. Demographic and clinical data were obtained using standardized questionnaires. Anxiety, depression, and fatigue were assessed using the Beck Anxiety Inventory (BAI), Geriatric Depression Scale (GDS), and Fatigue Scale-14 (FS-14), respectively. Binary logistic regression identified risk factors for anxiety and depression, whereas Spearman's correlation assessed associations with fatigue.
resultsAnxiety and depression prevalence rates were 64.2% (mean BAI score: 19.59 ± 10.92) and 56.1% (mean GDS score: 12.82 ± 6.37), respectively. The mean FS-14 total score was 9.46 ± 1.89, comprising physical (5.77 ± 1.51) and mental (3.69 ± 1.20) fatigue components. Significant positive correlations were observed between fatigue scores (total, physical, and mental) and both anxiety and depression (all
conclusionElderly PD patients show high rates of anxiety and depression, both of which are significantly correlated with fatigue severity. These findings highlight the importance of psychological monitoring and targeted mental health interventions in PD management among the elderly.
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