Evidence map›Paper›PMID 41557124›Full record

ArticleOphthalmology and therapy2026

Consensual Ophthalmotonic Reaction in Fellow Eyes in the Early Postoperative Period Following Unilateral Glaucoma Surgery.

Zhen Yang, Weijia Zhang, Jing Hong, Chun Zhang

Abstract read
In one paragraph

Article in Ophthalmology and therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Zhen YangDepartment of Ophthalmology, Peking University Third Hospital, Peking University Eye Center, No. 49, North Garden Street, Haidian District, Beijing, China.
Weijia ZhangBeijing Tsinghua Changgung Hospital Eye Center, School of Clinical Medicine, Tsinghua Medicine, Tsinghua University, No. 168 Litang Road, Changping District, Beijing, 102218, China.
Jing HongDepartment of Ophthalmology, Peking University Third Hospital, Peking University Eye Center, No. 49, North Garden Street, Haidian District, Beijing, China. hongjing1964@sina.com.
Chun ZhangBeijing Tsinghua Changgung Hospital Eye Center, School of Clinical Medicine, Tsinghua Medicine, Tsinghua University, No. 168 Litang Road, Changping District, Beijing, 102218, China. zhangc1@yahoo.com.ORCID http://orcid.org/0000-0001-5203-8463

Funding

Natural Science Foundation of Beijing Municipality L234016
6 · The paper itself

Abstract

introductionConsensual ophthalmotonic reaction (COR) refers to consensual intraocular pressure (IOP) change in the fellow eye following alteration of IOP in one eye. The study aimed to investigate COR and the magnitude of consensual IOP change after unilateral glaucoma surgery.

methodsWe analyzed 356 eyes from 293 patients who underwent unilateral trabeculectomy, bleb needling, trabectome, or microcatheter-assisted trabeculectomy (MAT) between 2016 and 2022. In the fellow eye, baseline IOP was compared with IOP at 1 day, 1 week, 1 months, 3 months, and 6 months postoperatively. Fellow eyes with IOP change exceeding 4 mmHg or 20% increase from baseline were defined as fellow eyes with COR. Univariate and multivariate analysis were performed to identify influencing factors associated with COR and IOP change in the fellow eye.

resultsIn fellow eyes, IOP was 18.3 ± 7.3 mmHg at baseline, significantly increasing to 19.3 ± 7.5 mmHg at postoperative day 1 (POD1) and remaining stable at other time points, with a COR incidence of 40.7% (145 eyes) at POD1. Univariate and multivariate analysis identified preoperative use of α

conclusionsCollectively, our findings suggest that COR is a common early postoperative phenomenon regardless of glaucoma surgery type, and the preoperative use of α

Indexed as

Consensual ophthalmotonic reactionFellow eyeGlaucoma surgeryIntraocular pressureα2-receptor agonists

Identifiers

PMID41557124
PMCPMC12901754

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.