Evidence map›Paper›PMID 41557128›Full record

ReviewMolecular and cellular biochemistry2026

Advances in MicroRNA-Based Therapies for Cardiac Repair: Emerging Strategies for Treating Myocardial Infarction.

Ambreen Iqbal, Muhammad Waseem Ghani, Nannan Shao, Ye Zhang, Zixun Wang, Renjun Pei

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular and cellular biochemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ambreen IqbalSchool of Nano-Tech and Nano-Bionics, University of Science and Technology of China, Hefei, 230026, China.
Muhammad Waseem GhaniSchool of Nano-Tech and Nano-Bionics, University of Science and Technology of China, Hefei, 230026, China.
Nannan ShaoJiangsu Key Laboratory of Organoid Engineering and Precision Medicine, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou, 215123, China.
Ye ZhangSchool of Nano-Tech and Nano-Bionics, University of Science and Technology of China, Hefei, 230026, China. yezhang2017@sinano.ac.cn.
Zixun WangSchool of Nano-Tech and Nano-Bionics, University of Science and Technology of China, Hefei, 230026, China. zixunwang2021@sinano.ac.cn.
Renjun PeiSchool of Nano-Tech and Nano-Bionics, University of Science and Technology of China, Hefei, 230026, China. rjpei2011@sinano.ac.cn.

Funding

Science and Technology Foundation of Jiangsu Province BE2023731, BK20232046Science and Technology Foundation of Suzhou SZS2023006
6 · The paper itself

Abstract

Myocardial infarction (MI) continues to be a major cause of mortality worldwide, highlighting the need for immediate investigation into novel therapeutic approaches for repairing damaged heart tissue. MicroRNAs (miRNAs) have become essential regulators of different biological processes, including heart development, MI development, and cardiac repair after MI. This review seeks to elucidate the complex functions of miRNAs in MI development and cardiac regeneration/repair after MI, emphasizing their role in regulating different stages related to MI, such as inflammation, apoptosis, angiogenesis, and fibrosis. We also reviewed the advances in the regulation of particular miRNAs in the MI and their potential as therapeutic agents for evaluating cardiac recovery. Furthermore, we summarised the encouraging developments in miRNA-based therapeutics, in vitro growth of cardiomyocytes (CMs) for cell therapy of MI. Understanding the various functions that miRNAs perform in the heart's repair process following MI offers a great deal of promise for developing therapeutic approaches that can improve patient outcomes and mitigate the effects of heart failure.

Indexed as

MicroRNAsMyocardial InfarctionMyocytes, CardiacRegenerationAnimalsHumansMicroRNAsCardiac repairCell therapyMicroRNAsMyocardial infarction

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.