Evidence map›Paper›PMID 41557139›Full record

ArticleLa Radiologia medica2026

Proximal plaque cap morphology in femoropopliteal occlusion affects the primary patency of endovascular therapy: a CT angiography cohort study.

Yanzi Li, Ningning Ding, Xinzhou Xie, Longlong Cong, Jian Dong, Yang Han, Lin Yang

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Article in La Radiologia medica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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5 · Who and what money

Authors and funding

7 authors.

Yanzi LiCenter of Public Health, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Ningning DingDepartment of Radiology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Xinzhou XieDepartment of Information Engineering, School of Electronics and Information, Northwestern Polytechnical University, Xi'an, China.
Longlong CongDepartment of Vascular Surgery, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Jian DongDepartment of Vascular Surgery, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Yang HanDepartment of Vascular Surgery, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Lin YangDepartment of Vascular Surgery, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China. jdvascs@163.com.

Funding

Natural Science Foundation of China 82370459
6 · The paper itself

Abstract

purposeThis study aimed to investigate the effect and potential mechanism of plaque morphology on primary patency after endovascular therapy for femoropopliteal occlusion (FPO). MATERIALS AND

methodsA total of 355 FPO patients were divided into four groups based on the chronic total occlusion crossing approach and plaque cap morphology (CTOP) classification. The volume of the plaque cap, calcification score and hemodynamic simulation were calculated on the basis of the CT angiography images, and the effect of cap morphology on primary patency was assessed at 12 months after therapy.

resultsProximal concave cap lesions (CTOPs I & II) were associated with fewer retrograde punctures and flow-limiting dissections (p < 0.05). Although there was no difference in primary patency or freedom from CD-TLR among the CTOP classifications, the primary patency of proximal concave cap was significantly greater than that of convex cap (81.7 vs. 72.9%; p = 0.04); the freedom from CD-TLR of proximal concave cap was significantly higher than that of convex cap (91.4 vs. 81.4%; p = 0.006). Moreover, the proximal concave cap had a smaller plaque volume than the convex cap (26.00 ± 25.77 mm

conclusionsThe proximal concave plaque cap of the FPO indicates a smaller cap volume and lower degree of severe calcification, which helps to determine endovascular therapy strategy before procedure.

Indexed as

Arterial Occlusive DiseasesComputed Tomography AngiographyEndovascular ProceduresFemoral ArteryPlaque, AtheroscleroticPopliteal ArteryVascular PatencyAgedFemaleHumansMaleMiddle AgedRetrospective StudiesEndovascular therapyFemoropopliteal arteryOcclusion lesionPlaque morphologyPrimary patency

Identifiers

PMID41557139

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.