Evidence mapPaperPMID 41557692Full record

ArticlePloS one2026

Impact of health literacy and medication adherence on achieving blood pressure goals among hypertensive patients at the University of Gondar Comprehensive Specialized Referral Hospital, Northwest Ethiopia.

Alemante Tafese Beyna, Assefa Kebad Mengesha, Habtamu Semagne Ayele, Firomsen Mamuye Dajane, Abreham Honelgn Mule, Assefa Belay Asrie, Tafere Mulaw Belete, Demis Getachew, Tekletsadik Tekleslassie Alemayehu, Gebresilassie Tadesse and 3 more

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Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

13 authors.

Alemante Tafese BeynaDepartment of Pharmacology, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.ORCID https://orcid.org/0009-0003-9867-5443
Assefa Kebad MengeshaDepartment of Pharmacology, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Habtamu Semagne AyeleDepartment of Pharmacology, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Firomsen Mamuye DajaneDepartment of Pharmacology, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Abreham Honelgn MuleDepartment of Pharmacology, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Assefa Belay AsrieDepartment of Pharmacology, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Tafere Mulaw BeleteDepartment of Pharmacology, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Demis GetachewDepartment of Pharmacology, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Tekletsadik Tekleslassie AlemayehuDepartment of Social and Administrative Pharmacy, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Gebresilassie TadesseDepartment of Psychiatry, School of Medicine, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Gebremariam Wulie GeremewDepartment of Clinical Pharmacy, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.ORCID https://orcid.org/0009-0000-6691-8568
Liknaw Workie LimenhDepartment of Pharmaceutics, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Gizachew Kassahun BizunehDepartment of Pharmacognosy, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study assessed hypertensive health literacy and its association with achieving blood pressure goals at the University of Gondar Comprehensive Specialized Hospital, Ethiopia.

methodA cross-sectional study was conducted with 393 hypertensive patients from September 1 to October 30, 2024, selected through simple random sampling. Data were analyzed using t-tests, one-way ANOVA, and logistic regression, with p < 0.05 considered significant.

resultAmong the 393 participants, only 40.2% of participant achieved their blood pressure goal. Only 15% and 30.8% had high hypertensive health literacy and adherence levels, respectively. Participants living in an urban area (AOR = 5.1, 95% CI: 2.74-9.17, p < 0.001), with higher education (AOR = 2.7, 95% CI: 1.15-6.75, p < 0.023), living with hypertension for more than 10 years (AOR = 3.4, 95% CI: 1.54-7.58, p < 0.002), using three or more antihypertensive drugs (AOR = 0.3, 95% CI: 0.13-0.95, p < 0.041), adhering to treatment (AOR = 2.7, 95% CI: 1.34-5.55, p < 0.005), and having high hypertension health literacy (AOR = 3.8, 95% CI: 1.36-10.90, p < 0.011) were more likely to achieve blood pressure goal. Variables like residence (p < 0.001), marital status (p < 0.004), educational status (p < 0.013), occupation (p < 0.013), number of antihypertensive medications (p < 0.001), and presence of complication (p < 0.002) showed a significantly mean difference in hypertension health literacy score. There is a significant association between hypertensive health literacy and medication adherence with a p-value of < 0.001.

conclusionMost participants did not achieve their target blood pressure goals. Hypertensive health literacy and medication adherence were significantly associated with blood pressure goals. To improve these outcomes, health policies should focus on creating community-based educational programs that empower patients with a better understanding of their condition and the importance of following their treatment plans. Additionally, increasing access to healthcare resources and support can provide the guidance patients need to manage their hypertension effectively. By strengthening these initiatives, we can help more individuals take control of their health and achieve better blood pressure management.

Indexed as

Antihypertensive AgentsBlood PressureDrug MonitoringHealth LiteracyHypertensionMedication AdherenceAdultAgedCross-Sectional StudiesEthiopiaFemaleHumansMaleMiddle AgedAntihypertensive Agents

Identifiers

PMID41557692
PMCPMC12818684

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.