Evidence map›Paper›PMID 41558086›Full record

ArticleJournal of inorganic biochemistry2026

Persulfidation of the zinc finger protein ZRANB2 modulates its RNA binding and alternative splicing function.

Matthew S Hursey, Abigail D Reitz, Samuel E Fidler, Sarah L J Michel

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of inorganic biochemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Matthew S HurseyDepartment of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, MD 21201-1180, USA.
Abigail D ReitzDepartment of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, MD 21201-1180, USA.
Samuel E FidlerDepartment of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, MD 21201-1180, USA.
Sarah L J MichelDepartment of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, MD 21201-1180, USA. Electronic address: smichel@rx.umaryland.edu.

Funding

The Role of Zinc Fingers in H2S SignalingR01GM139854 · NIGMS · UNIVERSITY OF MARYLAND BALTIMORE · PI MICHEL, SARAH L · 2020 to 2023
$1.5M
NIGMS NIH HHS R01 GM139854
6 · The paper itself

Abstract

Zinc finger Ran-binding domain-containing protein 2 (ZRANB2) is an RNA-binding protein that plays a key role in alternative splicing. It contains two N-terminal RanBP2-type ZF domains in which four cysteine residues coordinate Zn(II) in a tetrahedral geometry to afford proper folding and function. Persulfidation, a post-translational modification in which cysteine thiols (-SH) are converted to persulfides (-SSH) by hydrogen sulfide (H

Indexed as

Alternative SplicingRNARNA-Binding ProteinsSulfidesHumansHydrogen SulfideProtein BindingZincZinc FingersHydrogen SulfidepersulfidesRNARNA-Binding ProteinsSulfidesZincZRANB2 protein, humanAlternative splicingHydrogen SulfidePersulfidationRNA bindingZinc fingerZRANB2

Identifiers

PMID41558086
PMCPMC13154102

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.