Evidence mapPaperPMID 41559528Full record

Trial reportObesity (Silver Spring, Md.)2026

Key Determinants of Weight Loss Trajectory Across Different Periods of a Behavioral Weight Loss Intervention.

Rocío De la Peña-Armada, Giovana Longo-Silva, María Rodríguez-Martín, Hui-Wen Yang, Marta Garaulet

Registry-linked trialAbstract readClinical Trial
In one paragraph

Trial report in Obesity (Silver Spring, Md.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02829619 (Meal Timing, Genetics and Weight Loss in a Mediterranean Population), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02829619 recruitingnot on this map

Meal Timing, Genetics and Weight Loss in a Mediterranean Population

TypeobservationalSponsorUniversidad de MurciaRan2008 to 2032Enrolled5,788ConditionsObesity
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rocío De la Peña-ArmadaDepartment of Nutrition and Food Science, Complutense University of Madrid, Madrid, Spain.
Giovana Longo-SilvaDepartment of Physiology, University of Murcia, Murcia, Spain.
María Rodríguez-MartínDepartment of Physiology, University of Murcia, Murcia, Spain.
Hui-Wen YangDivision of Sleep and Circadian Disorders, Departments of Medicine and Neurology, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Marta GarauletDepartment of Physiology, University of Murcia, Murcia, Spain.ORCID https://orcid.org/0000-0002-4066-3509

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 200160/2025-7Spanish Ministry of Science, Innovation and Universities PID2023-146183OB-I00
6 · The paper itself

Abstract

objectiveThis longitudinal study aims to identify the key factors influencing the weight loss trajectory during a 24-week intervention and their relevance at different stages of the treatment.

methodsWe studied 1252 participants (age 18-65 years) of a cognitive behavioral program to lose weight. Body weight was measured weekly, and a range of variables at baseline and throughout the treatment period were assessed. Linear regression analyses were conducted to understand the factors involved in the weight loss trajectory across three treatment periods (0-6, 7-12, 13-24 weeks).

resultsThe rate of weight loss progressively decreased from the 1st to the 3rd period (770-198 g/week). During the 1st period, the recent history of the individual, including baseline metabolic status, dietary habits, and motivation, was the highest-ranked determinant. In the 2nd period, the sole predictor was the long-term personal history of obesity, that is, the duration of the individual's lifetime spent with overweight/obesity. In the 3rd period, emotional eating behaviors and related barriers emerged as the two highest-ranked determinants of reduced rate of weight loss.

conclusionsFindings suggest targeted interventions that address the specific challenges of each period of weight loss interventions. As treatment progresses, strategies focused on emotional-related behaviors may be crucial for sustaining weight loss.

trial registrationClinicalTrials.gov identifier NCT02829619.

Indexed as

Cognitive Behavioral TherapyObesityWeight LossWeight Reduction ProgramsAdolescentAdultAgedFeeding BehaviorFemaleHumansLongitudinal StudiesMaleMiddle AgedMotivationOverweightYoung Adultbehavioral therapiesmotivationself‐monitoringweight loss

Identifiers

PMID41559528
PMCPMC12850559

What Socratic holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.