ArticleBMC pregnancy and childbirth2026
Association of uterine fibroids with adverse pregnancy outcomes: a retrospective cohort study.
Article in BMC pregnancy and childbirth, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo investigate the independent association between uterine fibroids and adverse pregnancy outcomes, and to explore the influence of fibroid characteristics, including type and location, on these risks.
methodsThis retrospective cohort study was conducted at a single tertiary hospital in Beijing, China, including all singleton deliveries between January 2022 and April 2023. A total of 2,118 pregnant women were enrolled, comprising 317 with uterine fibroids (fibroid group) and 1,801 without (control group). Maternal baseline characteristics, obstetric outcomes, and perinatal data were extracted from electronic medical records. Multivariable logistic regression analyses were performed to determine if uterine fibroids were independent risk factors for cesarean section, postpartum hemorrhage (PPH, ≥ 500 mL), and fetal malpresentation, after adjusting for potential confounders. Subgroup analyses were conducted to evaluate risks associated with fibroid size, number, type, and location.
resultsWomen in the fibroid group were significantly older (34.4 ± 3.7 vs. 32.1 ± 4.0 years, P < 0.001) and had higher rates of gestational diabetes mellitus, hypertensive disorders, severe preeclampsia, placenta previa, placental accreta spectrum, and anemia (all P < 0.05). In univariate analysis, the fibroid group had significantly higher rates of cesarean Sect. (54.9% vs. 42.0%, P < 0.001), PPH (28.1% vs. 7.3%, P < 0.001), and fetal malpresentation (5.0% vs. 2.6%, P = 0.018). After a more comprehensive adjustment for confounders, including placental disorders, uterine fibroids remained an independent risk factor for cesarean section (adjusted odds ratio [aOR] 1.52, 95% CI: 1.18–1.95), PPH (aOR 4.98, 95% CI: 3.69–6.72), and fetal malpresentation (aOR 1.99, 95% CI: 1.10–3.60). Subgroup analysis revealed that submucosal type, lower uterine segment location, large fibroids (≥ 5 cm), and multiple fibroids were associated with a significantly increased risk of adverse outcomes.
conclusionThe presence of uterine fibroids during pregnancy is a strong and independent risk factor for cesarean section, postpartum hemorrhage, and fetal malpresentation. Specific fibroid characteristics, such as submucosal type, lower segment location, large size, and multiplicity, further amplify these risks. These findings underscore the need for heightened antenatal surveillance and meticulous delivery planning for this high-risk population.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.