SynthesisMedicine2026
Visual bibliometric analysis of cytokines in the pathogenesis of cerebral palsy.
Synthesis in Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
backgroundCerebral palsy (CP) is the most common movement disorder in childhood, and its pathogenesis is complex, and cytokines have been shown to be involved in the pathological process of CP as key mediators, but the existing studies have been scattered and lack systematic summary.
objectiveReveal the research hotspots and cutting-edge trends of cytokines in the pathogenesis of CP.
methodsA systematic search was conducted in the Web of Science core database for relevant literature on the role of cytokines in the pathogenesis of CP. The CiteSpace and VOSviewer software were used to draw visual maps of authors, institutions, countries, and keywords.
resultsA total of 39 countries, 420 institutions and 1323 authors were identified. The United States led in the number of published articles and was the core of international cooperation. However, the cooperation among authors and institutions was still relatively loose. A total of 1527 keywords were involved. The high-frequency keywords include "inflammation," "periventricular leukomalacia," "necrosis-factor-alpha," etc. Cluster analysis divided the research into 4 categories: inflammation and immune response, perinatal injury, genetic regulation, and other potential associated factors. Emergent analysis shows that the research has gradually delved from basic factors such as early infection and birth weight to cytokine mechanisms and recent studies on inflammation and the child population.
conclusionsThe research on cytokines in the pathogenesis of CP focuses on core areas such as inflammation and immune response, perinatal injury, etc. The research has gradually delved from basic factors to mechanisms and inflammation studies in the pediatric population. In the future, we can pay attention to the dynamic evolution and development trend of these hot areas, optimize research directions and methods in a timely manner, and actively build a multi-dimensional and integrated research system related to cytokines and CP, so as to provide new ideas and strategies for early prevention, targeted therapy and precision rehabilitation of CP.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.