SynthesisMedicine2026
Efficacy of transmuscular quadratus lumborum block on postoperative nausea and vomiting: A meta-analysis of randomized controlled trials.
Synthesis in Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Anterior Quadratus Lumborum Block: A Scoping Review of Anatomical Rationale, Techniques, and Clinical Applications.Pain and therapy · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe use of transmuscular quadratus lumborum block (TQLB) offers potent pain relief in surgical interventions; nonetheless, the evidence is inadequate to prove its benefits in treating nausea and vomiting. This meta-analysis aimed to calculate the impact of TQLB on postoperative nausea and vomiting.
methodsTwo investigators carried out investigations for randomized controlled trials from Embase, PubMed, and the Cochrane Library, respectively. We used Review Manager software for the meta-analysis.
resultsTwelve trials with 725 patients were included. The incidences of postoperative nausea (risk ratio [RR]: 0.59, 95% confidence interval [CI]: 0.44-0.78) and postoperative vomiting (RR: 0.29, 95% CI: 0.09-0.88) in the TQLB group were notably less than those in the control group without publication bias as high-quality evidence evaluated by Grading of Recommendations Assessment, Development and Evaluation. TQLB could reduce the rest (standardized mean difference [SMD]: -0.53, 95% CI: -0.89 to -0.17) and activity (SMD: -0.48, 95% CI: -0.78 to -0.18). Numeric rating scale at the 6 hours after the operation, the rest and activity visual analogue scale (VAS) at both of the 6 hours (rest VAS: SMD: -1.01, 95% CI: -1.91 to -0.11; activity VAS: SMD: -0.89, 95% CI: -1.48 to -0.30) and 24 hours (rest VAS: SMD: -0.64, 95% CI: -1.15 to -0.12; activity VAS: SMD: -1.74, 95% CI: -2.39 to -1.10) after the surgery. TQLB could shorten the time to first ambulation (SMD: -0.54, 95% CI: -0.96 to -0.11), intestinal movement (SMD: -1.06, 95% CI: -1.43 to -0.69), and length of hospital stay (SMD: -0.89, 95% CI: -1.32 to -0.45). TQLB could notably decrease the incidence of rescue analgesia administration (RR: 0.49, 95% CI: 0.27-0.88) and increase the satisfaction degree (RR: 4.10, 95% CI: 2.41-6.99). The generalizability and interpretation of these results are constrained by the study's limited sample size, the exploratory analysis of secondary endpoints, and potential heterogeneity.
conclusionTQLB may decrease the incidence of postoperative nausea and vomiting, enhance postoperative pain management, accelerate postoperative recovery, and increase the satisfaction degree of patients. These benefits highlight the potential efficacy of TQLB to ensure safer and faster recovery following surgical procedures as high-quality evidence.
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