Evidence map›Paper›PMID 41560728›Full record

ArticleFrontiers in pharmacology2025

Preclinical pharmacological profiles of cofrogliptin, a novel and bi-weekly DPP-4 inhibitor.

Xiaoli Gou, Caixia Dou, Pingming Tang, Xiaoxiao Zheng, Chen Zhang, Jianmin Wang, Qingyuan Meng, Ju Wang

Abstract read
In one paragraph

Article in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xiaoli GouHaisco Pharmaceutical Group Co., Ltd., Chengdu, Sichuan, China.
Caixia DouHaisco Pharmaceutical Group Co., Ltd., Chengdu, Sichuan, China.
Pingming TangHaisco Pharmaceutical Group Co., Ltd., Chengdu, Sichuan, China.
Xiaoxiao ZhengHaisco Pharmaceutical Group Co., Ltd., Chengdu, Sichuan, China.
Chen ZhangHaisco Pharmaceutical Group Co., Ltd., Chengdu, Sichuan, China.
Jianmin WangHaisco Pharmaceutical Group Co., Ltd., Chengdu, Sichuan, China.
Qingyuan MengHaisco Pharmaceutical Group Co., Ltd., Chengdu, Sichuan, China.
Ju WangHaisco Pharmaceutical Group Co., Ltd., Chengdu, Sichuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: DPP-4 inhibitors are now established agents for glycaemic control in diabetes. Herein, this study systematically characterized cofrogliptin and elucidated its pharmacology, pharmacokinetics, and therapeutic efficacy for type 2 diabetes. Methods: Results: The findings have revealed that cofrogliptin is a potent and selective DPP-4 inhibitor with an IC Conclusion: Consequently, as the only approved bi-weekly DPP-4 inhibitor, cofrogliptin is well-positioned to substantially improve medication adherence among patients with type 2 diabetes, thereby improving therapeutic outcomes.

Indexed as

bi-weeklycofrogliptindipeptidyl peptidase 4DPP-4 inhibitorHSK7653long-actingtype 2 diabetes

Identifiers

PMID41560728
PMCPMC12812960

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.