ReviewMaterials today. Bio2026
PEDOT:PSS in peripheral nerve injury repair: electrical stimulation, neural interfaces, and neural regenerative mechanisms.
Review in Materials today. Bio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Injectable bioactive hydrogels as pharmacological drug delivery platforms for post-myocardial infarction cardiac repair: therapeutic cargo engineering, stimuli-responsive release mechanisms, and translational perspectives.Naunyn-Schmiedeberg's archives of pharmacology · 2026Review
- PEDOT: PSS for Implantable and Wearable Bioelectronics: From Material Engineering and Energy Storage to Clinical Translation.Small (Weinheim an der Bergstrasse, Germany) · 2026Review
- Advanced Functional Wound Dressings in Precision Surgery: Immunometabolic Reprogramming, Bioadaptive Biomaterials, and Intelligent Regenerative Interfaces.International journal of molecular sciences · 2026Review
- Method for Patterning of Conductive Polymers on Flexible Substrates with Possible Applications for Wearable Sensing.Micromachines · 2026Article
- Mechanisms and Applications of Conductive Biomaterials in Spinal Cord Injury Repair.Biomaterials research · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Peripheral nerve injury (PNI) remains a major clinical challenge due to the limited regenerative capacity of neural tissue. The conductive polymer (CP) poly(3,4-ethylenedioxythiophene):polystyrene sulfonate (PEDOT:PSS) has recently gained significant attention owing to its excellent electrochemical performance, biocompatibility, and mechanical flexibility. This review provides an overview of recent advances in PEDOT:PSS-based strategies for nerve repair, including nerve guide conduits (NGCs) and neural interfaces. Particular emphasis is placed on its roles in facilitating nerve regeneration via electrical stimulation (ES), enhancing the tissue-electrode interface, and improving functional recovery. The discussion also covers major obstacles to clinical translation, such as long-term stability, biodegradability, and immune response. Future efforts should focus on material modification, composite structure optimization, and the integration of three-dimensional (3D) printing and intelligent neural interface technologies to enable personalized and precise therapeutic applications. Overall, PEDOT:PSS represents a promising material for peripheral nerve regeneration (PNR) and offers new strategies for treating PNIs.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.