ReviewMaterials today. Bio2026
Biomaterial-assisted neuralization strategies for tissue engineering applications.
Review in Materials today. Bio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Extracellular Matrix Remodelling in the Human Sural Nerve in Peripheral Vascular Disease.Medicina (Kaunas, Lithuania) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In recent years, a large number of biomaterial-based strategies have been developed for tissue repair and regeneration. Despite these advances, achieving functional recovery of regenerated tissues remains a significant challenge, primarily because of insufficient attention to neuromodulation. This review provides a comprehensive analysis of biomaterial-assisted neuralization approaches aimed at repairing damaged tissues and restoring physiological function. We elucidate the mechanisms underlying neuralized tissue repair through four key aspects: the neural response following tissue injury or lesion, neurogenic inflammation and immune modulation, neurovascular coupling effects, and the effects of neuromodulation on stem cell behavior. Notably, smart-responsive and electroactive biomaterials have facilitated neuralization, thereby improving functional integration. Furthermore, this review highlights novel advances in biomaterial-assisted neuralization strategies for tissue engineering. The discussion is organized around four key perspectives: establishing structural and mechanical foundations conducive to neural regeneration, designing delivery systems for neural modulation, constructing microenvironments for electrophysiological regulation, and developing smart responsive biomaterials that facilitate neuralization. By examining current challenges and future directions, we provide innovative perspectives for the development of next-generation biomaterials to advance regenerative medicine.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.