ArticleFrontiers in veterinary science2025
Enhancing post-thaw sperm quality in rams: quinic acid as a natural antioxidant.
Article in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Liquid Storage and Cryopreservation of Ram Semen: Storage-Associated Damage and the Role of Non-Enzymatic Antioxidants.Veterinary sciences · 2026Review
- Dose-Dependent Effects of Protocatechuic Acid on Motility, Redox Balance, and DNA Integrity of Frozen-Thawed Ram Spermatozoa.International journal of molecular sciences · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: This study investigated the effects of quinic acid (QA) supplementation at different concentrations (Control, 50, 100, and 200 μg/mL) on the post-thaw quality of ram semen, with a focus on motility, DNA integrity, flow cytometric parameters, and oxidative status. Materials and methods: A total of 40 ejaculates collected from Ramlic rams were cryopreserved using Tris-based extenders containing QA. Post-thaw sperm quality was evaluated using Computer-Assisted Sperm Analysis (CASA), flow cytometry assays for viability, mitochondrial activity, and lipid peroxidation, and the single cell gel electrophoresis (COMET) analysis for DNA integrity. Oxidative status was assessed through measurements of TAS, TOS, MDA, and OSI. Results: QA supplementation at 100 μg/mL significantly improved total and progressive motility and enhanced key kinematic parameters compared with the control group ( Conclusion: In conclusion, QA exerted dose-dependent protective effects on sperm motility, viability, HMMP, and DNA stability during cryopreservation. The optimal concentration (100 μg/mL) effectively mitigated oxidative stress and improved post-thaw semen quality, suggesting that QA could serve as a promising antioxidant and cryoprotective additive for enhancing the success of artificial insemination programs in rams.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.