Evidence map›Paper›PMID 41561009›Full record

ArticleRSC advances2026

Novel diazenyl chalcones with a 2-arylidene hydrazineylidene thiazole moiety: synthesis, anticancer potential, spectroscopic characterisation, and molecular docking studies.

Mariem M El-Samoly, Esmail M El-Fakharany, Yousra A El-Maradny, Abdallah E Abdallah, F A Taher, Nadia T A Dawoud, Doaa R Lotfy

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mariem M El-SamolyChemistry Department, Faculty of Science, Girls, Al-Azhar University Nasr City Cairo Egypt.
Esmail M El-FakharanyProtein Research Department, Genetic Engineering and Biotechnology Research Institute, City of Scientific Research and Technological Applications (SRTA-City) New Borg AL-Arab 21934 Alexandria Egypt esmailelfakharany@yahoo.co.uk.
Yousra A El-MaradnyProtein Research Department, Genetic Engineering and Biotechnology Research Institute, City of Scientific Research and Technological Applications (SRTA-City) New Borg AL-Arab 21934 Alexandria Egypt esmailelfakharany@yahoo.co.uk.
Abdallah E AbdallahPharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University Nasr City Cairo 11884 Egypt dawoudnadia@yahoo.com.ORCID https://orcid.org/0000-0003-2597-7419
F A TaherChemistry Department, Faculty of Science, Girls, Al-Azhar University Nasr City Cairo Egypt.
Nadia T A DawoudChemistry Department, Faculty of Science, Girls, Al-Azhar University Nasr City Cairo Egypt.ORCID https://orcid.org/0000-0003-1852-7399
Doaa R LotfyChemistry Department, Faculty of Science, Girls, Al-Azhar University Nasr City Cairo Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A series of diazenyl chalcones bearing 2-arylidene-hydrazinylidene thiazole units (4-6a,b) were designed, synthesised, and fully characterised by NMR, IR, MS, and UV spectroscopy. The compounds were evaluated for cytotoxicity against normal skin cells and the MDA and HepG2 cancer cell lines. The results reveal that most synthetic chemicals exhibited limited toxicity on normal cells at concentrations of 100 µg mL

Identifiers

PMID41561009
PMCPMC12814023

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.