ArticleCureus2025
A Complex Diagnostic Challenge of Dual Antibiotic-Induced Drug Reaction With Eosinophilia and Systemic Symptoms (DRESS) Syndrome With Multiorgan Involvement.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a serious, immune-mediated hypersensitivity condition marked by cutaneous eruptions, fever, hematologic abnormalities, and involvement of multiple organ systems. We report a case of DRESS syndrome precipitated by IV vancomycin and minocycline, presenting with fever, diffuse morbilliform rash, marked eosinophilia, transaminitis, and acute kidney injury. The diagnostic process was challenging because of overlapping features between infectious and autoimmune etiologies, necessitating careful clinical correlation, medication review, and application of the Registry of Severe Cutaneous Adverse Reactions (RegiSCAR) criteria. Early recognition enabled prompt discontinuation of the offending agents and initiation of systemic corticosteroids, resulting in gradual improvement in hepatic and renal function. This case underscores the need to maintain a heightened clinical suspicion for DRESS syndrome in patients treated with high-risk antibiotics. It reinforces the importance of prompt recognition and coordinated multidisciplinary care to reduce the risk of lasting organ injury.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.