Evidence map›Paper›PMID 41561850›Full record

ArticleFrontiers in public health2025

Sarcopenia and the frailty progression among Chinese: a longitudinal study.

Xingyu Mu, Xia Wang, Qingyue Zeng, Xijie Yu, Shuangqing Li

Abstract read
In one paragraph

Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Observational
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xingyu MuGeneral Practice Ward, International Medical Center Ward, General Practice Medical Center, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Xia WangDepartment of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, China.
Qingyue ZengGeneral Practice Ward, International Medical Center Ward, General Practice Medical Center, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Xijie YuLaboratory of Endocrinology and Metabolism, Department of Endocrinology and Metabolism, Rare Disease Center, West China Hospital, Sichuan University, Chengdu, China.
Shuangqing LiGeneral Practice Ward, International Medical Center Ward, General Practice Medical Center, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Previous studies primarily focused on baseline sarcopenia status, neglecting changes over time. This study aims to explore the association between changes in sarcopenia status and frailty progression, hypothesizing that transitions to possible sarcopenia or sarcopenia increase frailty risk, while recovery to non-sarcopenia reduces this risk. Methods: Using data from the China Health and Retirement Longitudinal Study (CHARLS), sarcopenia was evaluated at baseline and after 2 years using the AWGS 2019 criteria. Frailty was assessed with a 32-item frailty index. Cox regression and linear mixed models analyzed the association between sarcopenia transitions and frailty progression. Results: Participants who developed possible sarcopenia or sarcopenia faced a 56% higher frailty risk (HR 1.56, 95% CI 1.21-2.01) and a faster frailty index increase ( Conclusion: Transitions in sarcopenia status significantly affect frailty risk and progression. Worsening sarcopenia heightens frailty risk, whereas recovery diminishes it. These findings highlight the value of monitoring and addressing sarcopenia in middle-aged and older adults, offering potential to enhance quality of life and lower healthcare costs through targeted interventions.

Indexed as

Frail ElderlyFrailtySarcopeniaAgedAged, 80 and overChinaDisease ProgressionEast Asian PeopleFemaleGeriatric AssessmentHumansLongitudinal StudiesMaleMiddle AgedRisk FactorsCHARLSdynamic natureepidemiologyfrailtysarcopenia

Identifiers

PMID41561850
PMCPMC12812598

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.