SynthesisFrontiers in psychiatry2025
Clinical efficacy study on the combined treatment of cancer-related depression with traditional Chinese acupuncture-related therapies and drugs.
Synthesis in Frontiers in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
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Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The incidence of cancer-related depression (CRD) is constantly increasing. Some clinical practice guidelines have pointed out that traditional Chinese acupuncture-related therapies can serve as an effective supplementary therapy to drug treatment for enhancing the therapeutic outcome. In this study, we systematically evaluated the therapeutic efficacy and clinical significance of different acupuncture-related therapies in the treatment of CRD. Methods: Three English databases (PubMed, Cochrane, and Web of Science) and three Chinese databases (VIP Chinese Science and Technology Journal Database, China National Knowledge Infrastructure, and Wanfang Database) were searched up to October 2024. The primary outcome measures were the total effective rate, the Self-Rating Depression Scale (SDS), and the Hamilton Depression Scale (HAM-D). Results: This study included 30 RCTs, encompassing 2,886 patients. Among them, 1,446 were in the control group and 1,440 in the experimental group. The primary outcome indicators revealed that compared with drug therapy alone, drug therapy combined with Traditional Chinese acupuncture-related therapies demonstrated significant advantages in terms of efficacy (OR = 3.74, 95% CI 2.83, 4.96; Conclusion: Traditional Chinese acupuncture-related therapies, especially auricular acupressure therapy, can assist drug treatment in relieving CRD. This research facilitates the development of complementary medicine, and is conducive to reducing drug resistance and enhancing the quality of life of patients. Systematic review registration: https://www.crd.york.ac.uk/prospero/, identifier CRD420251242774.
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