Evidence map›Paper›PMID 41563208›Full record

ArticleJACC. Case reports2026

Sarcoidosis Masquerading as Hypertrophic Cardiomyopathy.

Sanjay Sivalokanathan, Sharan J Kapadia, Philip Robson, Zahi Fayad, Adam Jacobi, Anuradha Lala, Sean Pinney, Valentin Fuster, Maria Giovanna Trivieri

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sanjay SivalokanathanMount Sinai, New York, New York, USA.
Sharan J KapadiaMount Sinai, New York, New York, USA.
Philip RobsonMount Sinai, New York, New York, USA.
Zahi FayadMount Sinai School of Medicine, New York, New York, USA.
Adam JacobiMount Sinai, New York, New York, USA.
Anuradha LalaMount Sinai, New York, New York, USA.
Sean PinneyMount Sinai, New York, New York, USA.
Valentin FusterMount Sinai School of Medicine, New York, New York, USA.
Maria Giovanna TrivieriMount Sinai, New York, New York, USA. Electronic address: mariagiovanna.trivieri@mountsinai.org.

Funding

MR/PET Imaging of coronary atherosclerosisR01HL071021 · NHLBI · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI FAYAD, ZAHI A. · 2002 to 2019
$7.8M
NHLBI NIH HHS R01 HL071021
6 · The paper itself

Abstract

backgroundHypertrophic cardiomyopathy (HCM) and infiltrative cardiomyopathies are important causes of cardiogenic syncope with overlapping clinical and radiologic features. CASE SUMMARY: A 49-year-old gentleman presented with syncope while walking across the Brooklyn Bridge. Electrocardiogram revealed low-voltage QRS with diffuse T-wave inversions. Echocardiography revealed moderate left ventricular hypertrophy, wall motion abnormalities with left ventricular ejection fraction 35% to 40%, and a dilated, hypokinetic right ventricle. Cardiac magnetic resonance showed biventricular hypertrophy and evidence of late gadolinium enhancement. Positron emission tomography/magnetic resonance (PET/MR) 18F-FDG revealed right ventricle uptake along with matching late gadolinium enhancement and FDG avidity in the hilar and mediastinal lymph nodes. Endomyocardial biopsy showed noncaseating granulomas, confirming sarcoidosis. An implantable cardioverter-defibrillator was inserted. Despite immunosuppression and guideline-directed medical treatment, the patient eventually required cardiac transplantation. DISCUSSION: Cardiac sarcoidosis mimicking genetic cardiomyopathy, and vice versa, has often been reported. Combined PET/MR helped distinguish these pathologies in our patient. TAKE-HOME MESSAGES: Cardiac sarcoidosis can mimic HCM; multimodal imaging, including PET/MR, guided by clinical suspicion, is important. Biventricular involvement in HCM is infrequent.

Indexed as

cardiac magnetic resonancecardiomyopathyhybrid imagingimagingpositron emission tomography

Identifiers

PMID41563208
PMCPMC12948608

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.