Evidence map›Paper›PMID 41563541›Full record

ReviewInsights into imaging2026

Photon-counting detector CT in oncology: a new era of cancer imaging.

Elisa Bruno, Anna Palmisano, Enrico Camisassa, Davide Vignale, Carlo Tacchetti, Antonio Esposito

Abstract readReview
In one paragraph

Review in Insights into imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Elisa Bruno *Advanced Imaging for Personalized Medicine Unit, Experimental Imaging Center, IRCCS San Raffaele Hospital, Milan, Italy.
Anna Palmisano *Advanced Imaging for Personalized Medicine Unit, Experimental Imaging Center, IRCCS San Raffaele Hospital, Milan, Italy. palmisano.anna@hsr.it.ORCID http://orcid.org/0000-0002-1564-2060
Enrico CamisassaAdvanced Imaging for Personalized Medicine Unit, Experimental Imaging Center, IRCCS San Raffaele Hospital, Milan, Italy.
Davide VignaleAdvanced Imaging for Personalized Medicine Unit, Experimental Imaging Center, IRCCS San Raffaele Hospital, Milan, Italy.
Carlo TacchettiVita-Salute San Raffaele University, Milan, Italy.
Antonio EspositoAdvanced Imaging for Personalized Medicine Unit, Experimental Imaging Center, IRCCS San Raffaele Hospital, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oncologic imaging plays a critical role in the diagnosis, staging, treatment planning, and follow-up of cancer patients. Recent advancements in computed tomography, particularly the development of photon-counting detector CT (PCCT), have introduced new opportunities for improving diagnostic accuracy and tissue characterization, while reducing contrast agent usage and radiation exposure. By offering ultra-high spatial resolution, enhanced contrast-to-noise ratio, and intrinsic spectral capabilities, PCCT addresses many limitations of conventional energy-integrating detector CT (EID-CT) and unlocks new possibilities for quantitative imaging. This review explores the emerging applications of PCCT across various tumor types-including thoracic, abdominal, and musculoskeletal malignancies-highlighting its potential to improve cancer imaging and patient care. CRITICAL RELEVANCE STATEMENT: Photon-counting detector CT (PCCT) offers several advantages in oncologic imaging, providing superior spatial resolution, spectral imaging capabilities, and reduced radiation dose, enhancing lesion characterization and precise treatment planning, making PCCT a valuable tool for personalized cancer care. KEY POINTS: CT has a crucial role in oncological imaging, supporting diagnosis, staging, treatment planning and follow-up. Compared to EID-CT, PCCT offers higher spatial and contrast resolution, reduces artifacts and image noise and provides spectral data enabling quantitative assessment. PCCT may improve cancer imaging by increasing diagnostic accuracy, with better detection of small lesions, enhanced soft tissue contrast, and enabling quantitative iodine uptake evaluation.

Indexed as

CancerEnergy integrated detector CTOncologyPhoton-counting detector CTSpectral

Identifiers

PMID41563541
PMCPMC12824093

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.