Evidence map›Paper›PMID 41563696›Full record

ReviewClinical rheumatology2026

Global research status and trends in the treatment of ankylosing spondylitis from 2005 to 2024: a bibliometric analysis.

Zhaoxia Zeng, Jiayi Zou, Jiawang Zhao, Yu Quan, Jie Liao, Yun Peng, Wugen Li

Abstract readReview
PubMed Publisher
In one paragraph

Review in Clinical rheumatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zhaoxia Zeng *Department of Radiology, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, 330006, Nanchang, China.
Jiayi Zou *Department of Radiology, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, 330006, Nanchang, China.
Jiawang ZhaoDepartment of Radiology, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, 330006, Nanchang, China.
Yu QuanDepartment of Radiology, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, 330006, Nanchang, China.
Jie LiaoDepartment of Radiology, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, 330006, Nanchang, China.
Yun PengDepartment of Radiology, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, 330006, Nanchang, China.
Wugen LiDepartment of Radiology, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, 330006, Nanchang, China. liwugen_ndefy@163.com.ORCID http://orcid.org/0009-0006-0726-019X

Funding

the Science and Technology Research Project of Education Department of Jiangxi Province No. GJJ2200121
6 · The paper itself

Abstract

This bibliometric analysis aimed to delineate the evolving research landscape and priorities in the treatment of ankylosing spondylitis, a chronic immune-mediated inflammatory disease. Publications were retrieved from the Web of Science Core Collection, including 6567 relevant articles published between 2005 and 2024 for quantitative and visual analysis. The annual publication output demonstrated consistent growth, with the United States and the Free University of Berlin identified as the most productive country and institution, respectively. Author analysis revealed that Van der Heijde D. was the most prolific contributor, demonstrating exceptional citation impact. Keyword co-occurrence analysis identified five major research clusters, including biological therapies, pathogenesis, disease assessment, epidemiology, and classification criteria. Furthermore, the key citation burst detection highlighted a strategic shift in research focus over time, with "axial spondyloarthritis" and "biological therapy" representing the most current frontiers. The intellectual landscape of ankylosing spondylitis treatment has evolved from tumor necrosis factor inhibitors to include interleukin-17 inhibitors, reflecting a deeper understanding of disease mechanisms. Future research is anticipated to increasingly explore precision medicine approaches and combination therapies.

Indexed as

BibliometricsBiomedical ResearchSpondylitis, AnkylosingHumansInterleukin-17Tumor Necrosis Factor-alphaInterleukin-17Tumor Necrosis Factor-alphaAnkylosing spondylitisBibliometricsBiologic therapyInterleukin-17Tumor necrosis factor

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.