Evidence mapPaperPMID 41564347Full record

Trial reportDiabetes care2026

Sleep Extension Improves Sleep Health but Not Insulin Sensitivity in People With Overweight or Obesity Who Maintain Habitual Short Sleep Schedules.

Joseph W Beals, Gordon I Smith, Sarah S Farabi, Bruce W Patterson, Brendan P Lucey, Josiane L Broussard, Kenneth P Wright, Samuel Klein

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Diabetes care, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Joseph W BealsCenter for Human Nutrition, Washington University in St. Louis School of Medicine, St. Louis, MO.
Gordon I SmithCenter for Human Nutrition, Washington University in St. Louis School of Medicine, St. Louis, MO.
Sarah S FarabiCenter for Human Nutrition, Washington University in St. Louis School of Medicine, St. Louis, MO.
Bruce W PattersonCenter for Human Nutrition, Washington University in St. Louis School of Medicine, St. Louis, MO.
Brendan P LuceyDepartment of Neurology, Washington University in St. Louis School of Medicine, St. Louis, MO.
Josiane L BroussardDepartment of Health and Exercise Science, Colorado State University, Fort Collins, CO.
Kenneth P WrightDepartment of Integrative Physiology, University of Colorado, Boulder, CO.
Samuel KleinCenter for Human Nutrition, Washington University in St. Louis School of Medicine, St. Louis, MO.ORCID 0000-0001-7127-1156

Funding

Washington University Institute of Clinical and Translational SciencesUL1TR002345 · WASHINGTON UNIVERSITY · 2025 to 2025
$9.3M
PILOT STUDY--SUBSTRATE METABOLISM IN EXTREMELY LOW BIRTH WEIGHT INFANTSP30DK048520 · UNIVERSITY OF COLORADO DENVER · 1995 to 2025
$7.7M
Washington University Nutrition Obesity Research CenterP30DK056341 · WASHINGTON UNIVERSITY · 1999 to 2025
$5.7M
WU P&FP30DK020579 · NIDDK · WASHINGTON UNIVERSITY · 2022 to 2025
$5.6M
WUSTL Transdisciplinary Pre- and Postdoctoral Training Program in Obesity and Cardiovascular DiseaseT32HL130357 · WASHINGTON UNIVERSITY · 2025 to 2025
$275k
NCATS NIH HHS UL1 TR002345NHLBI NIH HHS T32 HL130357NIDDK NIH HHS P30 DK020579NIDDK NIH HHS P30 DK048520NIDDK NIH HHS P30 DK056341NIDDK NIH HHS R01 DK115502NIH HHS T32 HL130357NIH HHS UL1 TR000448
6 · The paper itself

Abstract

objectiveTo determine whether extending sleep improves insulin sensitivity in people with overweight or obesity, insulin resistance, and habitual short sleep schedules (<7 h/night). RESEARCH DESIGN AND

methodsParticipants were randomized to habitual sleep (HS) (n = 15) or extended sleep (ES) (n = 14) for ∼6 weeks. Multiorgan (whole-body [primarily muscle], hepatic, and adipose tissue) insulin sensitivity (assessed by the hyperinsulinemic-euglycemic clamp procedure with tracer infusions) and glycemic control (assessed by 24-h serial plasma glucose and insulin concentrations during wakefulness) were determined.

resultsTime in bed and sleep duration increased more in the ES group (1.3 ± 0.6 and 1.1 ± 0.5 h/night) than in the HS group (0.3 ± 0.8 and 0.0 ± 0.4 h/night). Day-to-day variability in sleep and subjective measures of sleep health improved more in the ES than HS group, without differences in multiorgan insulin sensitivity or glycemic control between groups.

conclusionsExtending sleep by ∼1 h/night for ∼6 weeks in people with overweight or obesity and short sleep schedules improves sleep health but not insulin sensitivity or glycemic control.

Indexed as

Insulin ResistanceObesityOverweightSleepAdultBlood GlucoseFemaleGlucose Clamp TechniqueHumansInsulinMaleMiddle AgedSleep DurationBlood GlucoseInsulin

Identifiers

PMID41564347
PMCPMC13094871

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.