ArticleVaccine2026
Comparative effectiveness and cost-effectiveness of policies for provisioning rabies post-exposure vaccines.
Article in Vaccine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Clinic-based characteristics of animal-related injury presentations in Hangzhou, China: a 10-year retrospective analysis.Frontiers in public health · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors.
Funding
Abstract
introductionThe burden of rabies remains high in low-income countries, where limited access to life-saving post-exposure prophylaxis (PEP) leads to preventable deaths. Lack of evidence on the implications of PEP provisioning strategies impedes policy development. We evaluate three PEP strategies under consideration in Tanzania, comparing current limited access, improved access with free provision, and free provision combined with Integrated Bite Case Management (IBCM).
methodsWe examined data from IBCM implementation on PEP delivery practices, healthcare-seeking, and rabies risk across four Tanzanian regions. Using these data within a decision tree model, we evaluate health outcomes and economic impacts of proposed PEP policies from the healthcare provider perspective, projecting vaccine requirements, costs, and deaths across Tanzania over a five-year period (2026-2030).
resultsWe project approximately 59,000 (95 % PI: 32,000-96,000) rabies exposures nationwide over five years. With this exposure risk, current PEP access leads to around 800 deaths annually (95 % PI: 400-1200). Improved PEP access increases patients starting PEP, driving vaccine requirements to around 24,000 (95 % CI: 14,000-34,000) vials per year and reducing deaths by >40 %. Introducing IBCM reduces total projected deaths over 2026-2030 from 2300 to 2000 while remaining highly cost-effective at $181 per death averted.
conclusionTanzania's current PEP practice fails to meet the demand for rabies prevention, leading to preventable deaths. Free PEP is a more effective alternative, and implementing IBCM would further strengthen the country's rabies response and accelerate progress toward the target to end human rabies deaths by 2030.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.