Evidence map›Paper›PMID 41565812›Full record

ArticleNature2026

Convergent evolution of scavenger cell development at brain borders.

Andrea U Gaudi, Michelle Meier, Oguzhan F Baltaci, Sayali Chowdhary, Frank J Tulenko, Stefanie Dudczig, Sebastian-Alexander Stamatis, Scott Paterson, Hujun Yu, Maria Cristina Rondon Galeano and 12 more

Abstract read
In one paragraph

Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Engulfment by brain macrophages in a short-lived vertebrate.bioRxiv : the preprint server for biology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Andrea U GaudiPeter MacCallum Cancer Centre, Melbourne, Victoria, Australia.ORCID 0000-0003-1723-6880
Michelle MeierPeter MacCallum Cancer Centre, Melbourne, Victoria, Australia.
Oguzhan F BaltaciPeter MacCallum Cancer Centre, Melbourne, Victoria, Australia.
Sayali ChowdharyCardiovascular Research Institute, Weill Cornell Medicine, New York, NY, USA.ORCID 0000-0002-2570-9978
Frank J TulenkoAustralian Regenerative Medicine Institute, Monash University, Clayton, Victoria, Australia.
Stefanie DudczigPeter MacCallum Cancer Centre, Melbourne, Victoria, Australia.ORCID 0000-0003-0048-7261
Sebastian-Alexander StamatisAustralian Regenerative Medicine Institute, Monash University, Clayton, Victoria, Australia.
Scott PatersonPeter MacCallum Cancer Centre, Melbourne, Victoria, Australia.
Hujun YuPeter MacCallum Cancer Centre, Melbourne, Victoria, Australia.ORCID 0000-0003-3746-0695
Maria Cristina Rondon GaleanoPeter MacCallum Cancer Centre, Melbourne, Victoria, Australia.
Elizabeth MasonPeter MacCallum Cancer Centre, Melbourne, Victoria, Australia.
Lee B MilesSchool of Biological Sciences, Monash University, Clayton, Victoria, Australia.ORCID 0000-0002-2718-1353
Robert J Bryson-RichardsonSchool of Biological Sciences, Monash University, Clayton, Victoria, Australia.ORCID 0000-0002-9501-8208
Andrew J PaskTIGRR Lab, School of BioSciences, The University of Melbourne, Parkville, Victoria, Australia.ORCID 0000-0002-1900-2263
Jana VukovicSchool of Biomedical Sciences, Faculty of Medicine, The University of Queensland, St Lucia, Queensland, Australia.ORCID 0000-0002-3739-1688
Anne K LagendijkDivision of Genomics of Development and Disease, Institute for Molecular Bioscience, The University of Queensland, St Lucia, Queensland, Australia.ORCID 0000-0003-1246-1608
Kelly A SmithDepartment of Anatomy and Physiology, University of Melbourne, Melbourne, Victoria, Australia.ORCID 0000-0002-8283-9760
Jan KaslinAustralian Regenerative Medicine Institute, Monash University, Clayton, Victoria, Australia.
Michael Rm HarrisonCardiovascular Research Institute, Weill Cornell Medicine, New York, NY, USA.
Peter D CurrieAustralian Regenerative Medicine Institute, Monash University, Clayton, Victoria, Australia.ORCID 0000-0001-8874-8862
Neil I BowerDivision of Genomics of Development and Disease, Institute for Molecular Bioscience, The University of Queensland, St Lucia, Queensland, Australia.
Benjamin M HoganPeter MacCallum Cancer Centre, Melbourne, Victoria, Australia. ben.hogan@petermac.org.ORCID 0000-0002-0651-7065

Funding

Lymphatic Support of Neurogenesis and RegenerationR01NS126209 · NINDS · WEILL MEDICAL COLL OF CORNELL UNIV · PI Michael Harrison · 2023 to 2026
$1.8M
ARCAustralian Research CouncilBright Focus Foundation USANational Health and Medical Research CouncilNINDS NIH HHS R01 NS126209
6 · The paper itself

Abstract

The vertebrate central nervous system is protected by the blood-brain barrier and meningeal membranes, which ensure immune privilege

Indexed as

Biological EvolutionBrainZebrafishAnimalsBlood-Brain BarrierCadherinsCell DifferentiationCell LineageEndothelial CellsFemaleHumansMacrophagesMaleMiceMicrogliaTranscription FactorsCadherinsTranscription FactorsZebrafish Proteins

Identifiers

PMID41565812
PMCPMC12999481

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.