ReviewEuropean journal of medical research2026
Neuroplasticity mechanisms of NDBIs in autism: a review from brain connectivity to behavioral improvement.
Review in European journal of medical research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Asynchronous Social Communication Development in Autism: A Component-Level Analysis.Journal of autism and developmental disorders · 2026Article
- Adaptive Behavior Change in Autism: Outcomes from a Comprehensive, Interdisciplinary Clinical Care Cohort.Journal of personalized medicine · 2026Article
- GABAFrontiers in pharmacology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition characterized by deficits in social communication and interaction. In recent years, Naturalistic Developmental Behavioral Interventions (NDBI), particularly the Early Start Denver Model (ESDM), have demonstrated significant efficacy in enhancing social cognitive functions in children with autism. This review synthesizes current neuroimaging research on ESDM and related NDBI approaches, with a focus on how these interventions promote neuroplasticity by remodeling brain connectivity within social cognitive networks. We examine the neural substrates underlying behavioral improvements and discuss the critical factors influencing intervention outcomes, including timing, intensity, and duration. By integrating findings on brain network reorganization and functional enhancement, this article aims to provide theoretical insights and practical guidance for optimizing clinical interventions and informing future research directions in ASD treatment.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.