ArticlePerioperative medicine (London, England)2026
Programmed intermittent paravertebral bolus infusion reduces the incidence of postoperative chronic pain three months after thoracoscopic surgery in elderly patients: an observational study.
Article in Perioperative medicine (London, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectivesThe aim of this study was to examine the association between programmed intermittent paravertebral bolus infusion and chronic post-surgical pain (CPSP), including pain components and pain distribution, following video-assisted thoracoscopic surgery (VATS) in elderly patients.
designAn Observational Study.
settingThis study was conducted at Beijing Chest Hospital, Capital Medical University.
participantsElderly patients undergoing VATS.
interventionsPatients in the paravertebral group received programmed intermittent paravertebral bolus infusion with local anesthetics postoperatively, while patients in the intravenous group received patient controlled intravenous analgesia (PCIA) with sufentanil. MEASUREMENTS AND MAIN
resultsCPSP in our study was defined according to the International Classification of Diseases (ICD-11). Among the 242 elderly patients, Group P had a lower incidence of persistent pain at 3 months postoperatively compared to Group I (3.5% versus 13.4%, p = 0.014). Group P also had a lower incidence of anterior chest pain than Group I at both 1 month (p = 0.005) and 3 months (p = 0.020) postoperatively. Additionally, at 3 months, Group P had a lower incidence of neuropathic pain than the Group I (p = 0.021). Furthermore, Group P demonstrated reduced rates of pricking pain and hyperesthesia compared to Group I (p = 0.024; p = 0.042).
conclusionsProgrammed intermittent paravertebral bolus infusion reduces the incidence of postoperative chronic pain in patients undergoing thoracic surgery. It also decreases the occurrence of neuropathic pain three months after surgery.
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