ArticleAmerican journal of cardiovascular disease2025
Pre-transplant hemodynamic profiles of patients with ischemic vs. non-ischemic cardiomyopathy: insights from a retrospective single-center study.
Article in American journal of cardiovascular disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Superior 5-Year Survival in Heart Transplant Recipients with Pre-Transplant Dilated Cardiomyopathy Versus Ischemic Cardiomyopathy.Diagnostics (Basel, Switzerland) · 2026Article
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Abstract
objectivesHeart transplantation remains the last resort for patients with end-stage heart failure. The clinical and hemodynamic profiles of these patients may differ depending on the underlying etiology of cardiomyopathy. This study aimed to evaluate pre-transplant hemodynamic characteristics in patients with ischemic versus non-ischemic cardiomyopathy.
methodsWe conducted a retrospective analysis of 170 adult patients who underwent orthotopic heart transplantation at a single center. Patients were categorized based on the etiology of heart failure as either ischemic or non-ischemic cardiomyopathy. Preoperative hemodynamic and echocardiographic parameters were compared between the groups.
resultsOf the 170 patients, 45.2% had ischemic cardiomyopathy. These patients were significantly older than those with non-ischemic cardiomyopathy (53.2 vs. 46.7 years, P<0.01). However, no significant differences were observed between the two groups in pulmonary capillary wedge pressure (17.9 ± 8.0 vs. 17.4 ± 9.5 mmHg), mean pulmonary artery pressure (29.4 ± 10.9 vs. 27.3 ± 12.6 mmHg), or left ventricular ejection fraction (21.4 ± 10.8% vs. 23.3 ± 12.5%).
conclusionWhile ischemic cardiomyopathy patients were older, their preoperative hemodynamic and echocardiographic profiles were closely similar to those with non-ischemic cardiomyopathy.
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