Evidence mapPaperPMID 41567845Full record

ArticleAmerican journal of cardiovascular disease2025

Deep learning models for predicting heart disease risk using the UCI database: methods, performance, and clinical context.

Reza Khademi, Golnaz Yazdanpanah, Ghazaleh Rouhparvarzamin, Vida Hafezi, Shayesteh Haghighi, Parham Panahi, Aida Bakhshi, Bita Faridnia, Ramin Ahangar-Sirous, Yasaman Tavakoli and 7 more

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Article in American journal of cardiovascular disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

17 authors.

Reza KhademiStudent Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences Mashhad, Iran.
Golnaz YazdanpanahSchool of Medicine, Shiraz University of Medical Sciences Shiraz, Iran.
Ghazaleh RouhparvarzaminStudent Research Committee, School of Nursing and Midwifery, Shahid Sadoughi University of Medical Sciences Yazd, Iran.
Vida HafeziSchool of Medicine, Alborz University of Medical Sciences Karaj, Iran.
Shayesteh HaghighiDepartment of Nursing, School of Nursing and Midwifery, Ahvaz Jundishapur University of Medical Sciences Ahvaz, Iran.
Parham PanahiKazan Federal University Kazan, Russian Federation.
Aida BakhshiFaculty of Medicine, Mashhad University of Medical Sciences Mashhad, Iran.
Bita FaridniaDepartment of Internal Medicine, Shahid Beheshti University of Medical Sciences Tehran, Iran.
Ramin Ahangar-SirousStudent Research Committee, Tabriz University of Medical Sciences Tabriz, Iran.
Yasaman TavakoliMedical Student, Department of Medicine, Mazandaran University of Science Sari, Iran.
Mohammad Amin KarimiSchool of Medicine, Shahid Beheshti University of Medical Sciences Tehran, Iran.
Farzad SheikhzadehSchool of Medicine, Iran University of Medical Sciences Tehran, Iran.
Ata Akhtari KohnehshahriStudent Research Committee, Faculty of Medicine, Tabriz Medical Sciences, Islamic Azad University Tabriz, Iran.
Amir AbdiStudent Research Committee, School of Medicine, Tehran Medical Sciences, Islamic Azad University Tehran, Iran.
Shekoufeh SafarbeiranvandStudent Research Committee, School of Medicine, Islamic Azad University Kerman, Iran.
Mahsa Asadi AnarCollege of Medicine, University of Arizona Tucson, AZ, USA.
Parisa Alsadat DadkhahStudent Research Committee, School of Medicine, Isfahan University of Medical Sciences Isfahan, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo develop and evaluate deep learning models for predicting heart disease using the University of California, Irvine (UCI) heart disease dataset, and to contextualize model performance against classical machine learning approaches.

methodData were extracted from the University of California Irvine (UCI) heart disease dataset, including information from Cleveland, Hungary, Switzerland, and Long Beach V, collected in 1988. The dataset comprises 1,025 patients and 14 key attributes. Deep learning models were used to analyze the data and predict heart disease risk.

resultsThe deep learning models demonstrated high accuracy in predicting heart disease risk. The Random Forest model achieved an accuracy of 99%. Significant predictors included exercise-induced angina and downsloping ST segments. The data revealed that 72% of females and 42% of males experienced heart attacks. There was a 79% chance that atypical angina and a 77% chance that non-anginal pain would lead to a heart attack. Exercise-induced angina had a 67% chance of resulting in a heart attack, while downsloping of the peak exercise ST segment had a 72% chance. Additionally, a 71% chance was observed for heart attacks in patients with no major coronary artery blockage (ca=0), and a 75% chance for those with a potentially reversible thalassemia-related defect (thal=2). Age groups 40-44 and 50-54 had a 76% and 61% risk of heart attacks, respectively.

conclusionDeep learning models can significantly enhance heart disease risk prediction, leading to improved treatment strategies. These findings can aid in early diagnosis and timely interventions, improving clinical outcomes for heart disease patients.

Indexed as

cardiovascular risk factorsdeep learningHeart diseasemachine learningrandom forestrisk prediction

Identifiers

PMID41567845
PMCPMC12816779

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