Evidence map›Paper›PMID 41568549›Full record

ArticleJournal of the American Heart Association2026

Signal Recognition Granule Receptor Beta Subunit Promotes Arrhythmogenic Remodeling in the Heart Failure Mice.

Jingjing Zhang, Yucheng Pan, Yang Gong, Bin Kong, Tao Chen, Wei Shuai, He Huang

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jingjing ZhangDepartment of Cardiology Renmin Hospital of Wuhan University Wuhan Hubei People's Republic of China.
Yucheng PanDepartment of Cardiology Renmin Hospital of Wuhan University Wuhan Hubei People's Republic of China.
Yang GongDepartment of Cardiology Renmin Hospital of Wuhan University Wuhan Hubei People's Republic of China.
Bin KongDepartment of Cardiology Renmin Hospital of Wuhan University Wuhan Hubei People's Republic of China.
Tao ChenDepartment of Cardiology Renmin Hospital of Wuhan University Wuhan Hubei People's Republic of China.
Wei ShuaiDepartment of Cardiology Renmin Hospital of Wuhan University Wuhan Hubei People's Republic of China.
He HuangDepartment of Cardiology Renmin Hospital of Wuhan University Wuhan Hubei People's Republic of China.ORCID 0000-0002-5513-3922

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHeart failure is a major cause of global morbidity and mortality, often complicated by ventricular arrhythmias (VAs) that worsen prognosis. The

methodsMale C57BL/6 mice received tail vein injections of adeno-associated virus to cardiac-specifically overexpress or knock down

results

conclusions

Indexed as

Arrhythmias, CardiacHeart FailureVentricular RemodelingAnimalsCalcium-Calmodulin-Dependent Protein Kinase Type 2Cells, CulturedDisease Models, AnimalEndoplasmic Reticulum StressFibroblastsFibrosisMaleMiceMice, Inbred C57BLMyocytes, CardiacNF-kappa BSignal TransductionCalcium-Calmodulin-Dependent Protein Kinase Type 2NF-kappa BTlr4 protein, mouseToll-Like Receptor 4electrical remodelingheart failureSrprbstructural remodelingventricular arrhythmias

Identifiers

PMID41568549
PMCPMC13055490

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.