Evidence map›Paper›PMID 41569197›Full record

ArticleAsian Pacific journal of cancer prevention : APJCP2026

A Comparative Analysis of Peripheral Dose Measurement Between Apex and Agility Collimators in Linear Accelerators.

Minnu N Tomy, Shambhavi C, Sarath S Nair, Jyothi Nagesh, Shirley Lewis, Krishna Sharan, Sajeesh S Nair, Sumeer Hussain, Vani Lakshmi R

Abstract readComparative Study
In one paragraph

Article in Asian Pacific journal of cancer prevention : APJCP, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

9 authors.

Minnu N TomyMedical Radiation Physics Programme, Manipal College of Health Professions, Manipal Academy of Higher Education, Manipal-576104, Karnataka, India.
Shambhavi CMedical Radiation Physics Programme, Manipal College of Health Professions, Manipal Academy of Higher Education, Manipal-576104, Karnataka, India.ORCID 0000-0001-8862-4552
Sarath S NairDepartment of Radiation Oncology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal 576104, Karnataka, India.ORCID 0000-0002-0012-6020
Jyothi NageshDepartment of Radiation Oncology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal 576104, Karnataka, India.ORCID 0000-0003-4308-8404
Shirley LewisDepartment of Radiation Oncology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal 576104, Karnataka, India.ORCID 0000-0001-5306-1649
Krishna SharanDepartment of Radiotherapy, K S Hegde Cancer hospital NITTE university Deralakatte Mangalore India.
Sajeesh S NairDepartment of Radiotherapy, Dr K M Cherian Institute of Medical Sciences, Kallissery P.O, Chengannur, Kerala, India.
Sumeer HussainDepartment of Radiation oncology, AL Moosa Specialist Hospital AL Ahsa, Saudi Arabia.
Vani Lakshmi RDepartment of Health Technology and Informatics Prasanna School of Public Health, Manipal Academy of Higher Education, Manipal-576104, Karnataka, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of this study is to compare and evaluate peripheral dose (PD) distributions from Apex and Agility multileaf collimators (MLCs) in a linear accelerator at varying beam energies, field sizes, and depths for the optimization of radiotherapy safety and precision.

methodsPD values were determined with Semiflex and PinPoint ionization chambers at depths of 2, 4, 8, and 10 cm in a water phantom. Doses were measured at distances of 1 - 5 cm from the field edge, for photon beams of 6 FF, 6 FFF, 10 FF, and 15 FF MV, with field sizes of 5 × 5 cm² and 10 × 10 cm². The measurements were normalized to the central-axis dose.

resultsThe PD varied with depth and beam energy but decreased with increasing distance from the edge of the field. The PinPoint chamber consistently reported lower doses near the field edge (maximum of 63.6% and 66.4%) in Apex and Agility compared to the Semiflex chamber (89.7% and 87.9%) respectively. Agility MLC tended to deliver higher peripheral doses than apex, reaching as high as 87.9% at 10 cm depth and 1 cm distance whereas with Agility, the value was 65.9% under the same conditions.

conclusionThe PD depends on the design of the MLC, photon energy, depth and beam size. The consistent reduction in peripheral dose with Apex and FFF beams is an encouraging finding that supports their continued use in advanced radiotherapy techniques and clinical decision-making.

Indexed as

Particle AcceleratorsPhantoms, ImagingRadiometryRadiotherapy Planning, Computer-AssistedHumansPhotonsRadiotherapy DosageAgilityApexLinear AcceleratorMulti-Leaf CollimatorPeripheral Dose

Identifiers

PMID41569197
PMCPMC13418039

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.