ArticleVeterinary research communications2026
Effects of supplementing with Nigella sativa meal and selenium nano-particles on growth performance, immunity, microbial count, oxidative stability, and intestinal integrity-related gene expression in heat-stressed growing rabbits.
Article in Veterinary research communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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Who cites it
5 citing papers in PubMed.
- Recent Advances in the Treatment of Thyroid Pathologies with Selenium-Containing Compounds, Nanoparticles and Nanocomplexes Based on Selenium and Selenoproteins.Biological trace element research · 2026Review
- Dietary fermented orange peel and selenium nanoparticles improve antioxidant status, immunity, intestinal integrity, and growth performance in heat-stressed broilers.Poultry science · 2026Article
- Dietary L-Arginine and Zinc Oxide Nanoparticles Improve Growth Performance, Oxidative Status, Immunity, and Intestinal Integrity Indicators in Heat-Stressed Weaned Rabbits.Veterinary sciences · 2026Article
- Essential Oil Blend and Ascorbic Acid Supplementation Improves Performance, Semen Characteristics, Redox Balance, and Intestinal Integrity in Heat-Stressed Male Rabbits.Veterinary sciences · 2026Article
- Dietary Combined Thyme Meal andVeterinary sciences · 2026Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Heat stress severely impacts the performance of growing rabbits, compromising their survival and hampering the sustainability of rabbit farming. Therefore, this study investigated the effects of nano-selenium, Nigella sativa meal, and their mixture supplementation on immune responses, antioxidant activity, gut health, and growth performance in growing rabbits. One hundred male New Zealand White rabbits were equally divided into four groups, each with five replicates at 35 days of age (5 rabbits/replicate). The control group was fed on a basal diet (CON) while the other groups were fed a basal diet supplemented with Nigella sativa meal (NSM, 40 g/kg), Nano-selenium (Nano-Se, 0.1 mg/kg), and their mixture (Se-NSM), respectively. Results showed that exposure of growing rabbits to heat stress resulted in a significant deterioration in growth performance and immune-oxidative status. Additionally, feeding rabbits with Se-NSM enhanced body weight gain, carcass weight, and feed conversion ratio. Se-NSM supplementation increased the digestibility of dry matter, crude fiber, and crude protein, and increased the activity of lipase and trypsin enzymes. Superoxide dismutase (SOD), total antioxidant capacity (TAC) activity, and triiodothyronine (T3), IgA, and IgG levels increased, while malondialdehyde (MDA) decreased in rabbits receiving Se-NSM supplementation. Adding Se-NSM decreased triglycerides, cholesterol, and LDL levels, while increasing glucose, total protein, and AST levels in rabbits. Supplementing Se-NSM enhanced gut health via reducing pathogenic microbes counts and mucin-2 (MUC-2) and cationic amino acid transporter-1 (CAT-1) gene expression. These findings indicate that combining Nano-selenium-Nigella sativa meal enhanced the rabbits’ growth performance, immune response, and gut integrity during heat stress.
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