Evidence map›Paper›PMID 41569965›Full record

GuidelineKidney & blood pressure research2026

2025 KDIGO Executive Summary: Diagnosis and Management of Pediatric Autosomal Dominant Polycystic Kidney Disease.

Sanat Subhash, Amir Safadi, Ruhaan Bajpai, Rupesh Raina

Abstract readReviewPractice Guideline
In one paragraph

Guideline in Kidney & blood pressure research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sanat SubhashNortheast Ohio Medical University, Rootstown, Ohio, USA.
Amir SafadiAkron Nephrology Associates/Cleveland Clinic Akron General Medical Center, Akron, Ohio, USA.
Ruhaan BajpaiAkron Nephrology Associates/Cleveland Clinic Akron General Medical Center, Akron, Ohio, USA.
Rupesh RainaAkron Nephrology Associates/Cleveland Clinic Akron General Medical Center, Akron, Ohio, USA, rraina@akronchildrens.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited kidney disorder, affecting 1 in 400 to 1,000 people worldwide. These significant care requirements reflect the importance of early diagnosis and prevention for affected patients and the need for evidence-based guidelines for treatment protocols and best practice measures. The 2025 KDIGO guidelines build on earlier frameworks such as the 2019 International consensus statement on the diagnosis and management of ADPKD in children and young people to improve screening, monitoring, and treatment methodology for pediatric ADPKD patients. Young and adolescent patients face unique challenges to care from detection of asymptomatic disease progression to early-onset hypertension, alongside stress faced by caregivers and families. This executive summary synthesizes the updated 2025 KDIGO recommendations and supporting evidence to outline new advancements and provide a practical approach for pediatric nephrologists to support improved treatment and transition into adulthood.

Indexed as

Polycystic Kidney, Autosomal DominantAdolescentChildHumansPractice Guidelines as TopicHypertension managementKDIGO guidelinesPediatric autosomal dominant polycystic kidney diseaseTransition to adult care

Identifiers

PMID41569965
PMCPMC12948374

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.